Molecular and therapeutic insights of alpha-lipoic acid as a potential molecule for disease prevention

AK Tripathi, AK Ray, SK Mishra, SM Bishen… - Revista Brasileira de …, 2023 - Springer
Alpha-lipoic acid is an organic, sulfate-based compound produced by plants, humans, and
animals. As a potent antioxidant and a natural dithiol compound, it performs a crucial role in …

[HTML][HTML] Nutritional supplements and complementary therapies in polycystic ovary syndrome

S Alesi, C Ee, LJ Moran, V Rao, A Mousa - Advances in Nutrition, 2022 - Elsevier
Polycystic ovary syndrome (PCOS) affects 1 in 5 women of reproductive age, and is
characterized by menstrual irregularities, clinical or biochemical hyperandrogenism, and the …

Ultramicronized palmitoylethanolamide and luteolin supplement combined with olfactory training to treat post-COVID-19 olfactory impairment: a multi-center double …

A Di Stadio, L D'Ascanio, LA Vaira… - Current …, 2022 - benthamdirect.com
Background: Olfactory training is the only evidence-based treatment for post-viral olfactory
dysfunction. Smell disorders after SARS-CoV-2 infection have been attributed to …

Antioxidant Hydrogels: Antioxidant Mechanisms, Design Strategies, and Applications in the Treatment of Oxidative Stress‐Related Diseases

B Hu, Y Ouyang, T Zhao, Z Wang, Q Yan… - Advanced …, 2024 - Wiley Online Library
Oxidative stress is a biochemical process that disrupts the redox balance due to an excess
of oxidized substances within the cell. Oxidative stress is closely associated with a multitude …

[HTML][HTML] Alpha-Lipoic Acid: Biological Mechanisms and Health Benefits

F Superti, R Russo - Antioxidants, 2024 - mdpi.com
Alpha-lipoic acid (ALA) is a bioactive molecule with significant health effects. The biological
action of ALA has been ascribed to the characteristic antioxidant properties of the oxidized …

[HTML][HTML] pH and lipase-responsive nanocarrier-mediated dual drug delivery system to treat periodontitis in diabetic rats

L Wang, Y Li, M Ren, X Wang, L Li, F Liu, Y Lan… - Bioactive materials, 2022 - Elsevier
Precise and controlled drug delivery to treat periodontitis in patients with diabetes remains a
significant clinical challenge. Nanoparticle-based drug delivery systems offer a potential …

Role of oxidative stress in diabetes-induced complications and their management with antioxidants

H Singh, R Singh, A Singh, H Singh… - … of Physiology and …, 2024 - Taylor & Francis
Diabetes mellitus (DM) is a huge global health issue and one of the most studied diseases,
with a large global prevalence. Oxidative stress is a cytotoxic consequence of the excessive …

Diabetic nephropathy: significance of determining oxidative stress and opportunities for antioxidant therapies

M Darenskaya, S Kolesnikov, N Semenova… - International Journal of …, 2023 - mdpi.com
Diabetes mellitus (DM) belongs to the category of socially significant diseases with epidemic
rates of increases in prevalence. Diabetic nephropathy (DN) is a specific kind of kidney …

Effects of alpha lipoic acid on metabolic syndrome: a comprehensive review

N Najafi, S Mehri… - Phytotherapy …, 2022 - Wiley Online Library
Metabolic syndrome (MetS) is a multifactorial disease with medical conditions such as
hypertension, diabetes, obesity, dyslipidemia, and insulin resistance. Alpha‐lipoic acid (α …

An overview of the antioxidant effects of ascorbic acid and alpha lipoic acid (in liposomal forms) as adjuvant in cancer treatment

M Attia, EA Essa, RM Zaki, AA Elkordy - Antioxidants, 2020 - mdpi.com
Antioxidants are known to minimize oxidative stress by interacting with free radicals
produced as a result of cell aerobic reactions. Oxidative stress has long been linked to many …