Biginelli reaction: an overview

H Nagarajaiah, A Mukhopadhyay, JN Moorthy - Tetrahedron Letters, 2016 - Elsevier
Biginelli reaction involves acid-catalyzed one-pot synthesis of 3, 4-dihydropyrimidin-2 (1 H)-
ones (DHPMs) using easily-accessible starting materials, namely, aldehyde, active …

The Ugi reaction in polymer chemistry: syntheses, applications and perspectives

B Yang, Y Zhao, Y Wei, C Fu, L Tao - Polymer Chemistry, 2015 - pubs.rsc.org
The Ugi reaction, one of the most famous multicomponent reactions, has recently been
introduced into polymer chemistry as a novel, efficient and useful tool to prepare …

50th Anniversary Perspective: Polymer Functionalization

E Blasco, MB Sims, AS Goldmann, BS Sumerlin… - …, 2017 - ACS Publications
The translation of small molecule chemistries into efficient methodologies for polymer
functionalization spans several decades, enabling critical advances in soft matter materials …

Multicomponent combinatorial polymerization via the Biginelli reaction

H Xue, Y Zhao, H Wu, Z Wang, B Yang… - Journal of the …, 2016 - ACS Publications
A multicomponent combinatorial polymerization method has been exploited as a new
intersection between combinatorial chemistry, polymer chemistry, and organic chemistry …

Poly (vinyl alcohol) modified via the Hantzsch reaction for biosafe antioxidant self-healing hydrogel

S Pan, N Zhang, X He, Z Fang, Y Wu, Y Wei… - ACS Macro …, 2023 - ACS Publications
Efficient routes for the preparation of functional self-healing hydrogels from functional
polymers are needed. In this study, we developed a strategy to effectively produce a vanillin …

Imine-based multicomponent polymerization: Concepts, structural diversity and applications

P Stiernet, A Debuigne - Progress in Polymer Science, 2022 - Elsevier
Multicomponent reactions (MCRs) are remarkable one-pot combinatorial synthetic tools
involving at least three reactants whose nearly all atoms are incorporated in the final …

Preparation of water soluble and biocompatible AIE-active fluorescent organic nanoparticles via multicomponent reaction and their biological imaging capability

Z Long, M Liu, R Jiang, Q Wan, L Mao, Y Wan… - Chemical Engineering …, 2017 - Elsevier
Fluorescent organic nanoparticles (FONs) with aggregation-induced emission (AIE) features
have been extensively investigated for bio-imaging applications because of their unique AIE …

The dawn of polymer chemistry based on multicomponent reactions

R Kakuchi - Polymer Journal, 2019 - nature.com
This focus review documents the developments in polymer synthesis that involve
multicomponent reactions (MCRs) and related sequential reaction systems …

Multicomponent reactions and multicomponent cascade reactions for the synthesis of sequence‐controlled polymers

Z Zhang, Y You, C Hong - Macromolecular Rapid …, 2018 - Wiley Online Library
Control over the monomer sequence during polymerization has attracted great attention in
polymer science, but it remains a serious challenge. Recently, multicomponent reactions …

Discovery of new phenyl sulfonyl-pyrimidine carboxylate derivatives as the potential multi-target drugs with effective anti-Alzheimer's action: Design, synthesis, crystal …

S Manzoor, SK Prajapati, S Majumdar, MK Raza… - European Journal of …, 2021 - Elsevier
Alzheimer's disease (AD) is multifactorial, progressive neurodegeneration with impaired
behavioural and cognitive functions. The multitarget-directed ligand (MTDL) strategies are …