Ruminococcus gnavus: friend or foe for human health
EH Crost, E Coletto, A Bell… - FEMS Microbiology …, 2023 - academic.oup.com
Ruminococcus gnavus was first identified in 1974 as a strict anaerobe in the gut of healthy
individuals, and for several decades, its study has been limited to specific enzymes or …
individuals, and for several decades, its study has been limited to specific enzymes or …
[HTML][HTML] Pathobionts in inflammatory bowel disease: origins, underlying mechanisms, and implications for clinical care
The gut microbiota plays a significant role in the pathogenesis of both forms of inflammatory
bowel disease (IBD), namely Crohn's disease (CD) and ulcerative colitis (UC). While …
bowel disease (IBD), namely Crohn's disease (CD) and ulcerative colitis (UC). While …
[HTML][HTML] Butyrate's role in human health and the current progress towards its clinical application to treat gastrointestinal disease
K Hodgkinson, F El Abbar, P Dobranowski… - Clinical Nutrition, 2023 - Elsevier
Butyrate is a key energy source for colonocytes and is produced by the gut microbiota
through fermentation of dietary fiber. Butyrate is a histone deacetylase inhibitor and also …
through fermentation of dietary fiber. Butyrate is a histone deacetylase inhibitor and also …
Drivers and determinants of strain dynamics following fecal microbiota transplantation
Fecal microbiota transplantation (FMT) is a therapeutic intervention for inflammatory
diseases of the gastrointestinal tract, but its clinical mode of action and subsequent …
diseases of the gastrointestinal tract, but its clinical mode of action and subsequent …
The human gut microbiome: from association to modulation
Our understanding of the human gut microbiome continues to evolve at a rapid pace, but
practical application of thisknowledge is still in its infancy. This review discusses the type of …
practical application of thisknowledge is still in its infancy. This review discusses the type of …
[HTML][HTML] Colonization of the live biotherapeutic product VE303 and modulation of the microbiota and metabolites in healthy volunteers
Manipulation of the gut microbiota via fecal microbiota transplantation (FMT) has shown
clinical promise in diseases such as recurrent Clostridioides difficile infection (rCDI) …
clinical promise in diseases such as recurrent Clostridioides difficile infection (rCDI) …
A novel Ruminococcus gnavus clade enriched in inflammatory bowel disease patients
Background Inflammatory bowel disease (IBD) is characterized by chronic inflammation of
the gastrointestinal tract that is associated with changes in the gut microbiome. Here, we …
the gastrointestinal tract that is associated with changes in the gut microbiome. Here, we …
MUC2 and related bacterial factors: therapeutic targets for ulcerative colitis
D Yao, W Dai, M Dong, C Dai, S Wu - EBioMedicine, 2021 - thelancet.com
Abstract The mucin2 (MUC2) mucus barrier acts as the first barrier that prevents direct
contact between intestinal bacteria and colonic epithelial cells. Bacterial factors related to …
contact between intestinal bacteria and colonic epithelial cells. Bacterial factors related to …
Specific bacteria and metabolites associated with response to fecal microbiota transplantation in patients with ulcerative colitis
Background & Aims Fecal microbiota transplantation (FMT) can induce remission in patients
with ulcerative colitis (UC). In a randomized controlled trial of FMT in patients with active UC …
with ulcerative colitis (UC). In a randomized controlled trial of FMT in patients with active UC …
The super-donor phenomenon in fecal microbiota transplantation
Fecal microbiota transplantation (FMT) has become a highly effective bacteriotherapy for
recurrent Clostridium difficile infection. Meanwhile the efficacy of FMT for treating chronic …
recurrent Clostridium difficile infection. Meanwhile the efficacy of FMT for treating chronic …