Neuronal migration is a critical process in the development of the nervous system. Defects in
the migration of the neurons are associated with diseases like lissencephaly, subcortical …

Adult hippocampal neurogenesis is a prominent event in rodents. In species with longer life
expectancies, newly born cells in the adult dentate gyrus of the hippocampal formation are …

Doublecortin (DCX) is required for normal migration of neurons into the cerebral cortex,
since mutations in the human gene cause a disruption of cortical neuronal migration. To …

Once programmed to acquire a specific identity and function, cells rarely change in vivo.
Neurons of the mammalian central nervous system (CNS) in particular are a classic example …

X-linked lissencephaly is a severe brain malformation affecting males. Recently it has been
demonstrated that the doublecortin gene is implicated in this disorder. In order to study the …

This review will discuss adult hippocampal neurogenesis in wild mammals of different taxa
and outline similarities with and differences from laboratory animals. It begins with a review …

Bats are the only flying mammals and have well developed navigation abilities for 3D-space.
Even bats with comparatively small home ranges cover much larger territories than rodents …

Doublecortin (Dcx) is a microtubule‐associated protein expressed by migrating neuroblasts
in the embryo and in the adult subventricular zone (SVZ). The adult SVZ contains …

Variations in the extent of adult neurogenesis and natural and experimental factors
controlling it have been described in laboratory animals. The wide range of variation seen …

We have demonstrated that cortical cell autografts might be a useful therapy in two monkey
models of neurological disease: motor cortex lesion and Parkinson's disease. However, the …