Neuroimaging standards for research into small vessel disease—advances since 2013

M Duering, GJ Biessels, A Brodtmann, C Chen… - The Lancet …, 2023‏ - thelancet.com
Cerebral small vessel disease (SVD) is common during ageing and can present as stroke,
cognitive decline, neurobehavioural symptoms, or functional impairment. SVD frequently …

[HTML][HTML] Vascular cognitive impairment (VCI)

T Rundek, M Tolea, T Ariko, EA Fagerli, CJ Camargo - Neurotherapeutics, 2022‏ - Elsevier
Vascular cognitive impairment (VCI) is predominately caused by vascular risk factors and
cerebrovascular disease. VCI includes a broad spectrum of cognitive disorders, from mild …

The potential impact of neuroimaging and translational research on the clinical management of lacunar stroke

S Rudilosso, A Rodríguez-Vázquez, X Urra… - International journal of …, 2022‏ - mdpi.com
Lacunar infarcts represent one of the most frequent subtypes of ischemic strokes and may
represent the first recognizable manifestation of a progressive disease of the small …

Cerebral small vessel disease and vascular cognitive impairment: from diagnosis to management

MCZ Zotin, L Sveikata, A Viswanathan… - Current opinion in …, 2021‏ - journals.lww.com
SVD is the leading cause of VCI and is associated with substantial morbidity. Tackling
cardiovascular risk factors is currently the most effective approach to prevent cognitive …

Neuroimaging in dementia: more than typical Alzheimer disease

S Haller, HR Jäger, MW Vernooij, F Barkhof - Radiology, 2023‏ - pubs.rsna.org
Alzheimer disease (AD) is the most common cause of dementia. The prevailing theory of the
underlying pathology assumes amyloid accumulation followed by tau protein aggregation …

[HTML][HTML] Quantifying blood-brain barrier leakage in small vessel disease: review and consensus recommendations

MJ Thrippleton, WH Backes, S Sourbron… - Alzheimer's & …, 2019‏ - Elsevier
Cerebral small vessel disease (cSVD) comprises pathological processes of the small
vessels in the brain that may manifest clinically as stroke, cognitive impairment, dementia, or …

Framework for clinical trials in cerebral small vessel disease (FINESSE): a review

HS Markus, WM van Der Flier, EE Smith, P Bath… - JAMA …, 2022‏ - jamanetwork.com
Importance Cerebral small vessel disease (SVD) causes a quarter of strokes and is the most
common pathology underlying vascular cognitive impairment and dementia. An important …

Cerebral microbleeds: from depiction to interpretation

L Puy, M Pasi, M Rodrigues, SJ Van Veluw… - Journal of Neurology …, 2021‏ - jnnp.bmj.com
Cerebral microbleeds (CMBs) are defined as hypointense foci visible on T2*-weighted and
susceptible-weighted MRI sequences. CMBs are increasingly recognised with the …

Advanced MRI in cerebral small vessel disease

H Van Den Brink, FN Doubal… - International Journal of …, 2023‏ - journals.sagepub.com
Cerebral small vessel disease (cSVD) is a major cause of stroke and dementia. This review
summarizes recent developments in advanced neuroimaging of cSVD with a focus on …

Retinal imaging in Alzheimer's disease

CY Cheung, V Mok, PJ Foster, E Trucco… - Journal of Neurology …, 2021‏ - jnnp.bmj.com
Identifying biomarkers of Alzheimer's disease (AD) will accelerate the understanding of its
pathophysiology, facilitate screening and risk stratification, and aid in develo** new …