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Targeting vascular (endothelial) dysfunction
A Daiber, S Steven, A Weber… - British journal of …, 2017 - Wiley Online Library
Cardiovascular diseases are major contributors to global deaths and disability‐adjusted life
years, with hypertension a significant risk factor for all causes of death. The endothelium that …
years, with hypertension a significant risk factor for all causes of death. The endothelium that …
Dietary (poly) phenolics in human health: structures, bioavailability, and evidence of protective effects against chronic diseases
Human intervention trials have provided evidence for protective effects of various (poly)
phenol-rich foods against chronic disease, including cardiovascular disease …
phenol-rich foods against chronic disease, including cardiovascular disease …
Current evidence on the effect of dietary polyphenols intake on chronic diseases
Polyphenols are secondary metabolites of plants. They comprise several antioxidant
compounds and they are generally considered to be involved in the defense against human …
compounds and they are generally considered to be involved in the defense against human …
Main drivers of (poly) phenol effects on human health: metabolite production and/or gut microbiota-associated metabotypes?
Despite the high human interindividual variability in response to (poly) phenol consumption,
the cause-and-effect relationship between some dietary (poly) phenols (flavanols and olive …
the cause-and-effect relationship between some dietary (poly) phenols (flavanols and olive …
Polyphenols and human health: prevention of disease and mechanisms of action
Polyphenols are found ubiquitously in plants and their regular consumption has been
associated with a reduced risk of a number of chronic diseases, including cancer …
associated with a reduced risk of a number of chronic diseases, including cancer …
[HTML][HTML] Effects of chocolate, cocoa, and flavan-3-ols on cardiovascular health: a systematic review and meta-analysis of randomized trials
Background: There is substantial interest in chocolate and flavan-3-ols for the prevention of
cardiovascular disease (CVD). Objective: The objective was to systematically review the …
cardiovascular disease (CVD). Objective: The objective was to systematically review the …
Is flow-mediated dilation nitric oxide mediated? A meta-analysis
Flow-mediated dilation (FMD) is a noninvasive index of endothelial function and vascular
health in humans. Studies examining the role of nitric oxide (NO) are not conclusive. In this …
health in humans. Studies examining the role of nitric oxide (NO) are not conclusive. In this …
Cocoa and chocolate in human health and disease
Cocoa contains more phenolic antioxidants than most foods. Flavonoids, including catechin,
epicatechin, and procyanidins predominate in antioxidant activity. The tricyclic structure of …
epicatechin, and procyanidins predominate in antioxidant activity. The tricyclic structure of …
[HTML][HTML] Intake and time dependence of blueberry flavonoid–induced improvements in vascular function: a randomized, controlled, double-blind, crossover …
Background: There are very limited data regarding the effects of blueberry flavonoid intake
on vascular function in healthy humans. Objectives: We investigated the impact of blueberry …
on vascular function in healthy humans. Objectives: We investigated the impact of blueberry …
Flavonoids and platelet aggregation: A brief review
C Faggio, A Sureda, S Morabito… - European journal of …, 2017 - Elsevier
Platelets are small anucleated fragments derived from a megakaryocyte precursor. Platelets
play a key role in many physiological functions especially in hemostasis and wound healing …
play a key role in many physiological functions especially in hemostasis and wound healing …