Tumor hypoxia regulates immune escape/invasion: influence on angiogenesis and potential impact of hypoxic biomarkers on cancer therapies
R Abou Khouzam, K Brodaczewska, A Filipiak… - Frontiers in …, 2021 - frontiersin.org
The environmental and metabolic pressures in the tumor microenvironment (TME) play a
key role in molding tumor development by impacting the stromal and immune cell fractions …
key role in molding tumor development by impacting the stromal and immune cell fractions …
Designing and building oncolytic viruses
Oncolytic viruses (OVs) are engineered and/or evolved to propagate selectively in
cancerous tissues. They have a dual mechanism of action; direct killing of infected cancer …
cancerous tissues. They have a dual mechanism of action; direct killing of infected cancer …
Bioengineered cellular and cell membrane-derived vehicles for actively targeted drug delivery: so near and yet so far
Cellular carriers for drug delivery are attractive alternatives to synthetic nanoparticles owing
to their innate homing/targeting abilities. Here, we review molecular interactions involved in …
to their innate homing/targeting abilities. Here, we review molecular interactions involved in …
Harnessing nanotechnology for cardiovascular disease applications-a comprehensive review based on bibliometric analysis
Cardiovascular diseases (CVDs) remain the leading cause of health problems worldwide.
Nanotechnology, based on its unique properties, provides novel solutions to the diagnosis …
Nanotechnology, based on its unique properties, provides novel solutions to the diagnosis …
Basic mechanisms of vascularization in endometriosis and their clinical implications
MW Laschke, MD Menger - Human reproduction update, 2018 - academic.oup.com
BACKGROUND Vascularization is a major hallmark in the pathogenesis of endometriosis.
An increasing number of studies suggests that multiple mechanisms contribute to the …
An increasing number of studies suggests that multiple mechanisms contribute to the …
Therapeutic potential of endothelial colony-forming cells in ischemic disease: strategies to improve their regenerative efficacy
Cardiovascular disease (CVD) comprises a range of major clinical cardiac and circulatory
diseases, which produce immense health and economic burdens worldwide. Currently …
diseases, which produce immense health and economic burdens worldwide. Currently …
Exploring the crosstalk between endothelial cells, immune cells, and immune checkpoints in the tumor microenvironment: new insights and therapeutic implications
J Fang, Y Lu, J Zheng, X Jiang, H Shen, X Shang… - Cell Death & …, 2023 - nature.com
The tumor microenvironment (TME) is a highly intricate milieu, comprising a multitude of
components, including immune cells and stromal cells, that exert a profound influence on …
components, including immune cells and stromal cells, that exert a profound influence on …
[HTML][HTML] VEGF-induced intracellular Ca2+ oscillations are down-regulated and do not stimulate angiogenesis in breast cancer-derived endothelial colony forming cells
Endothelial colony forming cells (ECFCs) represent a population of truly endothelial
precursors that promote the angiogenic switch in solid tumors, such as breast cancer (BC) …
precursors that promote the angiogenic switch in solid tumors, such as breast cancer (BC) …
Oncolytic virus: A catalyst for the treatment of gastric cancer
J Wang, L Du, X Chen - Frontiers in Oncology, 2022 - frontiersin.org
Gastric cancer (GC) is a leading contributor to global cancer incidence and mortality.
According to the GLOBOCAN 2020 estimates of incidence and mortality for 36 cancers in …
According to the GLOBOCAN 2020 estimates of incidence and mortality for 36 cancers in …
Cell-based tracers as trojan horses for image-guided surgery
Surgeons rely almost completely on their own vision and palpation to recognize affected
tissues during surgery. Consequently, they are often unable to distinguish between different …
tissues during surgery. Consequently, they are often unable to distinguish between different …