AI-based protein structure databases have the potential to accelerate rare diseases research: AlphaFoldDB and the case of IAHSP/Alsin
Artificial intelligence (AI)-based protein structure databases are expected to have an impact
on drug discovery. Here, we show how AlphaFold could support rare diseases research …
on drug discovery. Here, we show how AlphaFold could support rare diseases research …
p130Cas/BCAR1 and p140Cap/SRCIN1 Adaptors: The Yin Yang in Breast Cancer?
G Centonze, D Natalini, V Salemme… - Frontiers in Cell and …, 2021 - frontiersin.org
p130Cas/BCAR1 is an adaptor protein devoid of any enzymatic or transcriptional activity,
whose modular structure with various binding motifs, allows the formation of multi-protein …
whose modular structure with various binding motifs, allows the formation of multi-protein …
P130cas-FAK interaction is essential for YAP-mediated radioresistance of non-small cell lung cancer
J Li, X Zhang, Z Hou, S Cai, Y Guo, L Sun, A Li… - Cell Death & …, 2022 - nature.com
Based on the RNA-sequencing data, previous studies revealed that extracellular matrix
receptor interaction and focal adhesion signaling pathways were enriched in radioresistant …
receptor interaction and focal adhesion signaling pathways were enriched in radioresistant …
[HTML][HTML] Interrupting specific hydrogen bonds between ELF3 and MED23 as an alternative drug resistance-free strategy for HER2-overexpressing cancers
SY Hwang, S Park, H Jo, SH Seo, KH Jeon… - Journal of Advanced …, 2023 - Elsevier
Introduction HER2 overexpression induces cancer aggression and frequent recurrences in
many solid tumors. Because HER2 overproduction is generally followed by gene …
many solid tumors. Because HER2 overproduction is generally followed by gene …
First-in-human, phase I single-ascending-dose study of the safety, pharmacokinetics, and relative bioavailability of selatinib, a dual EGFR-ErbB2 inhibitor in healthy …
M Wang, Y Kuang, L Gong, Y Hua, Q Pei, C Guo… - Investigational New …, 2020 - Springer
We assessed the pharmacokinetics and safety of a single oral administration of selatinib to
healthy Chinese subjects and evaluated the potential bioavailability advantage of selatinib …
healthy Chinese subjects and evaluated the potential bioavailability advantage of selatinib …
[PDF][PDF] Journal Homepage:-www. journalijar. com
IL STYLES - researchgate.net
Aim: Study the relationship between nursing academic staff engagement in work and
traditional and innovative leadership styles. Background: Work engagement contributes to …
traditional and innovative leadership styles. Background: Work engagement contributes to …
[CITATION][C] Exploration of new combinatorial therapy candidates for tongue squamous cell carcinomas
A Hmedat - 2022 - Dissertation, Halle (Saale), Martin …