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Physical and mechanical regulation of macrophage phenotype and function
Macrophages are tissue-resident immune cells that play a critical role in maintaining
homeostasis and fighting infection. In addition, these cells are involved in the progression of …
homeostasis and fighting infection. In addition, these cells are involved in the progression of …
The mechanobiology of aging
Aging is a complex, multifaceted process that induces a myriad of physiological changes
over an extended period of time. Aging is accompanied by major biochemical and …
over an extended period of time. Aging is accompanied by major biochemical and …
Modulation of macrophage phenotype by cell shape
Phenotypic polarization of macrophages is regulated by a milieu of cues in the local tissue
microenvironment. Although much is known about how soluble factors influence …
microenvironment. Although much is known about how soluble factors influence …
Micro-and nanopatterned topographical cues for regulating macrophage cell shape and phenotype
Controlling the interactions between macrophages and biomaterials is critical for modulating
the response to implants. While it has long been thought that biomaterial surface chemistry …
the response to implants. While it has long been thought that biomaterial surface chemistry …
Microfluidic heart on a chip for higher throughput pharmacological studies
We present the design of a higher throughput “heart on a chip” which utilizes a semi-
automated fabrication technique to process sub millimeter sized thin film cantilevers of soft …
automated fabrication technique to process sub millimeter sized thin film cantilevers of soft …
[HTML][HTML] Effect of negative pressure wound therapy on wound healing
Vacuum-assisted closure (VAC), sometimes referred to as microdeformational wound
therapy (MDWT) or negative pressure wound therapy (NPWT), has revolutionized wound …
therapy (MDWT) or negative pressure wound therapy (NPWT), has revolutionized wound …
Stimuli-responsive engineered living materials
Stimuli-responsive materials are able to undergo controllable changes in materials
properties in response to external cues. Increasing efforts have been directed towards …
properties in response to external cues. Increasing efforts have been directed towards …
Mechanotherapy: revisiting physical therapy and recruiting mechanobiology for a new era in medicine
It has long been thought that the effectiveness and efficiency of physical therapy would
improve if our understanding of the cell biology/biochemistry that participates in mechanics …
improve if our understanding of the cell biology/biochemistry that participates in mechanics …
Bridging the gap: from 2D cell culture to 3D microengineered extracellular matrices
Historically the culture of mammalian cells in the laboratory has been performed on planar
substrates with media cocktails that are optimized to maintain phenotype. However, it is …
substrates with media cocktails that are optimized to maintain phenotype. However, it is …
Performance of a multilayered small-diameter vascular scaffold dual-loaded with VEGF and PDGF
F Han, X Jia, D Dai, X Yang, J Zhao, Y Zhao, Y Fan… - Biomaterials, 2013 - Elsevier
The urgent needs of functional arterial replacements for curing the vascular system diseases
have been proposed for many years. However, an ideal small-diameter vascular scaffold …
have been proposed for many years. However, an ideal small-diameter vascular scaffold …