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Prediction of bio-sequence modifications and the associations with diseases
C Ao, L Yu, Q Zou - Briefings in Functional Genomics, 2021 - academic.oup.com
Modifications of protein, RNA and DNA play an important role in many biological processes
and are related to some diseases. Therefore, accurate identification and comprehensive …
and are related to some diseases. Therefore, accurate identification and comprehensive …
Research progress in protein posttranslational modification site prediction
Posttranslational modifications (PTMs) play an important role in regulating protein folding,
activity and function and are involved in almost all cellular processes. Identification of PTMs …
activity and function and are involved in almost all cellular processes. Identification of PTMs …
Multivariate approach for Alzheimer's disease detection using stationary wavelet entropy and predator-prey particle swarm optimization
Background: The number of patients with Alzheimer's disease is increasing rapidly every
year. Scholars often use computer vision and machine learning methods to develop an …
year. Scholars often use computer vision and machine learning methods to develop an …
iEnhancer-5Step: identifying enhancers using hidden information of DNA sequences via Chou's 5-step rule and word embedding
An enhancer is a short (50–1500bp) region of DNA that plays an important role in gene
expression and the production of RNA and proteins. Genetic variation in enhancers has …
expression and the production of RNA and proteins. Genetic variation in enhancers has …
iCarPS: a computational tool for identifying protein carbonylation sites by novel encoded features
Motivation Protein carbonylation is one of the most important oxidative stress-induced post-
translational modifications, which is generally characterized as stability, irreversibility and …
translational modifications, which is generally characterized as stability, irreversibility and …
Malsite-deep: prediction of protein malonylation sites through deep learning and multi-information fusion based on NearMiss-2 strategy
M Wang, L Song, Y Zhang, H Gao, L Yan… - Knowledge-Based Systems, 2022 - Elsevier
Malonylation is a new protein post-translational modification and regulates a variety of
cellular physiological processes. However, it is costly and time-consuming to identify …
cellular physiological processes. However, it is costly and time-consuming to identify …
Citrullination site prediction by incorporating sequence coupled effects into PseAAC and resolving data imbalance issue
Background: Post-translational modification is one of the bio-molecular mechanisms in living
organisms, which incorporate functional diversity in proteins as well as regulate cellular …
organisms, which incorporate functional diversity in proteins as well as regulate cellular …
predML-site: predicting multiple lysine PTM sites with optimal feature representation and data imbalance minimization
Identifying of post-translational modifications (PTM) is crucial in the study of computational
proteomics, cell biology, pathogenesis, and drug development due to its role in many bio …
proteomics, cell biology, pathogenesis, and drug development due to its role in many bio …
[HTML][HTML] mLysPTMpred: multiple lysine PTM site prediction using combination of SVM with resolving data imbalance issue
Post-translational modification (PTM) increases the functional diversity of proteins by
introducing new functional groups to the side chain of amino acid of a protein. Among all …
introducing new functional groups to the side chain of amino acid of a protein. Among all …
MDD-carb: a combinatorial model for the identification of protein carbonylation sites with substrate motifs
HJ Kao, SL Weng, KY Huang, FJ Kaunang… - BMC systems …, 2017 - Springer
Background Carbonylation, which takes place through oxidation of reactive oxygen species
(ROS) on specific residues, is an irreversibly oxidative modification of proteins. It has been …
(ROS) on specific residues, is an irreversibly oxidative modification of proteins. It has been …