Obesity and cancer: a current overview of epidemiology, pathogenesis, outcomes, and management

S Pati, W Irfan, A Jameel, S Ahmed, RK Shahid - Cancers, 2023‏ - mdpi.com
Simple Summary Obesity has been linked to several common cancers including breast,
colorectal, esophageal, kidney, gallbladder, uterine, pancreatic, and liver cancer. Obesity …

[HTML][HTML] Excess body weight: Novel insights into its roles in obesity comorbidities

X Zhang, S Ha, HCH Lau, J Yu - Seminars in cancer biology, 2023‏ - Elsevier
Excess body weight is a global health problem due to sedentary lifestyle and unhealthy diet,
affecting 2 billion population worldwide. Obesity is a major risk factor for metabolic diseases …

[HTML][HTML] Pathophysiology of obesity and its associated diseases

X **, T Qiu, L Li, R Yu, X Chen, C Li, CG Proud… - … Pharmaceutica Sinica B, 2023‏ - Elsevier
The occurrence of obesity has increased across the whole world. Many epidemiological
studies have indicated that obesity strongly contributes to the development of cancer …

Systematic review and meta-analysis of the impact of bariatric surgery on future cancer risk

RB Wilson, D Lathigara, D Kaushal - International journal of molecular …, 2023‏ - mdpi.com
The study aimed to perform a systematic review and meta-analysis of the evidence for the
prevention of future cancers following bariatric surgery. A systematic literature search of the …

Metabolic dysfunction and obesity‐related cancer: beyond obesity and metabolic syndrome

P Karra, M Winn, S Pauleck, A Bulsiewicz‐Jacobsen… - …, 2022‏ - Wiley Online Library
Objectives: The metabolic dysfunction driven by obesity, including hyperglycemia and
dyslipidemia, increases risk for develo** at least 13 cancer types. The concept of …

Adiposity and sex-specific cancer risk

M Rask-Andersen, E Ivansson, J Höglund, WE Ek… - Cancer Cell, 2023‏ - cell.com
Obesity is associated with several types of cancer and fat distribution, which differs
dramatically between sexes, has been suggested to be an independent risk factor. However …

Metformin: A dual-role player in cancer treatment and prevention

MA Galal, M Al-Rimawi, A Hajeer, H Dahman… - International journal of …, 2024‏ - mdpi.com
Cancer continues to pose a significant global health challenge, as evidenced by the
increasing incidence rates and high mortality rates, despite the advancements made in …

Molecular mechanisms of western diet-induced obesity and obesity-related carcinogenesis—A narrative review

D Lathigara, D Kaushal, RB Wilson - Metabolites, 2023‏ - mdpi.com
The present study aims to provide a narrative review of the molecular mechanisms of
Western diet-induced obesity and obesity-related carcinogenesis. A literature search of the …

Obesity and Inflammation Lead to Insulin Resistance and Cancer—A Systematic Review

M Shafiul Hossen, M Abdul Barek… - Obesity: Clinical, Surgical …, 2024‏ - Springer
Adipose tissue mass is increased in obese people due to the increasing size and number of
adipocytes. It significantly changes the adipocytokines and inflammatory mediators secretion …

C/EBPB-dependent adaptation to palmitic acid promotes tumor formation in hormone receptor negative breast cancer

XZ Liu, A Rulina, MH Choi, L Pedersen… - Nature …, 2022‏ - nature.com
Epidemiological studies have established a positive association between obesity and the
incidence of postmenopausal breast cancer. Moreover, it is known that obesity promotes …