Pattern recognition in the nucleation kinetics of non-equilibrium self-assembly
Inspired by biology's most sophisticated computer, the brain, neural networks constitute a
profound reformulation of computational principles,–. Analogous high-dimensional, highly …
profound reformulation of computational principles,–. Analogous high-dimensional, highly …
[HTML][HTML] The art of designing DNA nanostructures with CAD software
Since the arrival of DNA nanotechnology nearly 40 years ago, the field has progressed from
its beginnings of envisioning rather simple DNA structures having a branched, multi-strand …
its beginnings of envisioning rather simple DNA structures having a branched, multi-strand …
Spatiotemporal control of coacervate formation within liposomes
Liquid-liquid phase separation (LLPS), especially coacervation, plays a crucial role in cell
biology, as it forms numerous membraneless organelles in cells. Coacervates play an …
biology, as it forms numerous membraneless organelles in cells. Coacervates play an …
Models and simulations of structural DNA nanotechnology reveal fundamental principles of self-assembly
DNA is not only a centrally important molecule in biology: the specificity of bonding that
allows it to be the primary information storage medium for life has also allowed it to become …
allows it to be the primary information storage medium for life has also allowed it to become …
Branching crisscross polymerization of single-stranded dna slats
Controlling where and when self-assembly happens is crucial in both biological and
synthetic systems as it optimizes the utilization of available resources. We previously …
synthetic systems as it optimizes the utilization of available resources. We previously …
Differentiable molecular simulations for control and learning
Molecular dynamics simulations use statistical mechanics at the atomistic scale to enable
both the elucidation of fundamental mechanisms and the engineering of matter for desired …
both the elucidation of fundamental mechanisms and the engineering of matter for desired …
Hydrogen-Bonded Fibrous Nanotubes Assembled from Trigonal Prismatic Building Blocks
In reticular chemistry, molecular building blocks are designed to create crystalline open
frameworks. A key principle of reticular chemistry is that the most symmetrical networks are …
frameworks. A key principle of reticular chemistry is that the most symmetrical networks are …
Spatial control of irreversible protein aggregation
Liquid cellular compartments form in the cyto-or nucleoplasm and can regulate aberrant
protein aggregation. Yet, the mechanisms by which these compartments affect protein …
protein aggregation. Yet, the mechanisms by which these compartments affect protein …
Temperature protocols to guide selective self-assembly of competing structures
Multicomponent self-assembly mixtures offer the possibility of encoding multiple target
structures with the same set of interacting components. Selective retrieval of one of the …
structures with the same set of interacting components. Selective retrieval of one of the …
Probing the formation kinetics and thermodynamics with rationally designed analytical tools enables one-pot synthesis and purification of a tetrahedral DNA …
The development of robust analytical tools capable of probing the formation kinetics and
thermodynamics of DNA nanostructures is a crucial step toward better understanding and …
thermodynamics of DNA nanostructures is a crucial step toward better understanding and …