Light sheet fluorescence microscopy (LSFM) uses a thin sheet of light to excite only
fluorophores within the focal volume. Light sheet microscopes (LSMs) have a true optical …

The impact of light-sheet fluorescence microscopy (LSFM) is visible in fields as diverse as
developmental and cell biology, anatomical science, biophysics and neuroscience …

Light-sheet microscopy is an ideal technique for imaging large cleared samples; however,
the community is still lacking instruments capable of producing volumetric images of …

For the 1.7 million patients per year in the US who receive a new cancer diagnosis,
treatment decisions are largely based on histopathological specimen examinations …

Systems-level identification and analysis of cellular circuits in the brain will require the
development of whole-brain imaging with single-cell resolution. To this end, we performed …

Uncovering the mechanisms of virus infection and assembly is crucial for preventing the
spread of viruses and treating viral disease. The technique of single-virus tracking (SVT) …

Light-sheet fluorescence microscopy (LSFM) is a widely used technique for imaging cleared
tissue and living samples. However, high-performance LSFM systems are typically …

Traditional imaging systems exhibit a well-known trade-off between the resolution and the
field of view of their captured images. Typical cameras and microscopes can either “zoom in” …

For decades, biologists have relied on software to visualize and interpret imaging data. As
techniques for acquiring images increase in complexity, resulting in larger multidimensional …

The resolution of fluorescence microscopy images is limited by the physical properties of
light. In the last decade, numerous super-resolution microscopy (SRM) approaches have …