Glucocorticoids have profound and complex effects on the human immune response.
However, the precise mechanisms of the corticosteroid-induced immunoregulation in man …

Age Heredity Tobacco Smoking Influence of Allergy and Nonspecific Airway
Responsiveness on Lung Growth and Development in Early Life Allergyas a Risk Factor for …

Immunoglobulin heavy chain (IgH) class-switch recombination (CSR) replaces initially
expressed Cμ (IgM) constant regions (CH) exons with downstream CH exons. Stimulation of …

Infection by helminthic parasites can cause the polyclonal stimulation of IgE synthesis,
possibly via an enhanced production of interleukin‐4 (IL‐4), and this has been suggested to …

The hyperimmunoglobulin E recurrent-infection (Job) syndrome (HIE) is a congenital
disorder characterized by high serum IgE, chronic eczematoid dermatitis, and recurrent …

The status of suppressor T cells (Ts) was assessed in seven children with the hyper IgE
syndrome (recurrent staphylococcal infections, eczematous skin rash, and elevated serum …

Peripheral blood lymphocytes from 22 patients with atopic dermatitis, 17 age-matched
healthy controls, 10 patients with other skin diseases, and 14 patients with either asthma or …

Once considered only mediators of inflammation, autacoids,(histamine, prostaglandins and
beta-mimetic catecholamines) have been found to be generated during specific early and …

Peripheral blood mononuclear leukocytes (MNL) from patients with atopic dermatitis
spontaneously produce large amounts of IgE in vitro. These cells also show markedly …

This paper describes an improved microtiter solid-phase enzyme immunoassay for the
determination of total and allergen-specific human IgE. This assay technique is unique in its …