Mechanical state transitions in the regulation of tissue form and function
From embryonic development, postnatal growth and adult homeostasis to reparative and
disease states, cells and tissues undergo constant changes in genome activity, cell fate …
disease states, cells and tissues undergo constant changes in genome activity, cell fate …
Passive and active microrheology for biomedical systems
Y Mao, P Nielsen, J Ali - Frontiers in bioengineering and …, 2022 - frontiersin.org
Microrheology encompasses a range of methods to measure the mechanical properties of
soft materials. By characterizing the motion of embedded microscopic particles …
soft materials. By characterizing the motion of embedded microscopic particles …
Multimodal microscale mechanical map** of cancer cells in complex microenvironments
The mechanical phenotype of the cell is critical for survival following deformations due to
confinement and fluid flow. One idea is that cancer cells are plastic and adopt different …
confinement and fluid flow. One idea is that cancer cells are plastic and adopt different …
Quantitative analysis of non-equilibrium systems from short-time experimental data
Estimating entropy production directly from experimental trajectories is of great current
interest but often requires a large amount of data or knowledge of the underlying dynamics …
interest but often requires a large amount of data or knowledge of the underlying dynamics …
Microtubule disassembly by caspases is an important rate-limiting step of cell extrusion
A Villars, A Matamoro-Vidal, F Levillayer… - nature …, 2022 - nature.com
The expulsion of dying epithelial cells requires well-orchestrated remodelling steps to
maintain tissue sealing. This process, named cell extrusion, has been mostly analysed …
maintain tissue sealing. This process, named cell extrusion, has been mostly analysed …
Recent Advances of Optical Tweezers–Based Dynamic Force Spectroscopy and Mechanical Measurement Assays for Live-Cell Mechanobiology
Cells sense and respond to mechanical stimuli for activation, proliferation, migration, and
differentiation. The associated mechanosensing and biomechanical properties of cells and …
differentiation. The associated mechanosensing and biomechanical properties of cells and …
Vascular regulation of disseminated tumor cells during metastatic spread
Cancer cells can travel to other organs via interconnected vascular systems to form new
lesions in a process known as metastatic spread. Unfortunately, metastasis remains the …
lesions in a process known as metastatic spread. Unfortunately, metastasis remains the …
E-cadherin adhesion dynamics as revealed by an accelerated force ramp are dependent upon the presence of α-catenin
Tissue remodeling and shape changes often rely on force-induced cell rearrangements
occurring via cell-cell contact dynamics. Epithelial cell-cell contact shape changes are …
occurring via cell-cell contact dynamics. Epithelial cell-cell contact shape changes are …
Optical tweezers across scales in cell biology
Optical tweezers (OT) provide a noninvasive approach for delivering minute physical forces
to targeted objects. Controlling such forces in living cells or in vitro preparations allows for …
to targeted objects. Controlling such forces in living cells or in vitro preparations allows for …
[HTML][HTML] α-Catenin Dependent E-cadherin Adhesion Dynamics as Revealed by an Accelerated Force Ramp
Tissue remodeling and shape changes often rely on force-induced cell rearrangements
occurring via cell-cell contact dynamics. Epithelial cell-cell contact shape changes are …
occurring via cell-cell contact dynamics. Epithelial cell-cell contact shape changes are …