Microorganisms, particularly extremophiles, have evolved multiple adaptation mechanisms
to address diverse stress conditions during survival in unique environments. Their …

Highlights•Systematic approaches can improve the efficiency of host selection and
development.•Tier System for Host Development is used to guide development of nonmodel …

Abstract Protocatechuic acid (3, 4-dihydroxybenzoic acid, PCA) is widely used in the
pharmaceuticals, health food, and cosmetics industries owing to its diverse biological …

Cis, cis-muconic acid (MA) is widely used as a key starting material in the synthesis of
diverse polymers. The growing demand in these industries has led to an increased need for …

The efficient production of biobased organic acids is crucial to move to a more sustainable
and eco-friendly economy, where muconic acid is gaining interest as a versatile platform …

Dicarboxylic acid (DCA) is a multifaceted chemical intermediate, recoursed to produce many
industrially important products such as adhesives, plasticizers, lubricants, polymers, etc. To …

Microbial production of organic acids has been hindered by the poor acid tolerance of
microorganisms and the high costs of waste salt reprocessing. The robustness of non …

Due to its potential use in the production of new functional resins, bio-plastics, food
additives, agrochemicals, and pharmaceuticals, muconic acid (MA), a high value-added bio …

Muconic acid (MA) is a valuable dicarboxylic acid with three isomers that are extensively
utilized in textile and chemical industries. Traditionally, the chemical synthesis of MA …

Reactive liquid–liquid extraction is an attractive, innovative technique to intensify the
fermentative production and downstream processing of biobased organic acids through a …