Optogenetics for light control of biological systems
Optogenetic techniques have been developed to allow control over the activity of selected
cells within a highly heterogeneous tissue, using a combination of genetic engineering and …
cells within a highly heterogeneous tissue, using a combination of genetic engineering and …
Probing neural codes with two-photon holographic optogenetics
H Adesnik, L Abdeladim - Nature neuroscience, 2021 - nature.com
Optogenetics ushered in a revolution in how neuroscientists interrogate brain function.
Because of technical limitations, the majority of optogenetic studies have used low spatial …
Because of technical limitations, the majority of optogenetic studies have used low spatial …
Optogenetics at the presynapse
Optogenetic actuators enable highly precise spatiotemporal interrogation of biological
processes at levels ranging from the subcellular to cells, circuits and behaving organisms …
processes at levels ranging from the subcellular to cells, circuits and behaving organisms …
[HTML][HTML] Magnetoelectric effect: principles and applications in biology and medicine–a review
S Kopyl, R Surmenev, M Surmeneva, Y Fetisov… - Materials Today Bio, 2021 - Elsevier
Magnetoelectric (ME) effect experimentally discovered about 60 years ago remains one of
the promising research fields with the main applications in microelectronics and sensors …
the promising research fields with the main applications in microelectronics and sensors …
Towards translational optogenetics
Optogenetics is widely used to interrogate the neural circuits underlying disease and has
most recently been harnessed for therapeutic applications. The optogenetic toolkit consists …
most recently been harnessed for therapeutic applications. The optogenetic toolkit consists …
BiPOLES is an optogenetic tool developed for bidirectional dual-color control of neurons
Optogenetic manipulation of neuronal activity through excitatory and inhibitory opsins has
become an indispensable experimental strategy in neuroscience research. For many …
become an indispensable experimental strategy in neuroscience research. For many …
Structural basis for channel conduction in the pump-like channelrhodopsin ChRmine
ChRmine, a recently discovered pump-like cation-conducting channelrhodopsin, exhibits
puzzling properties (large photocurrents, red-shifted spectrum, and extreme light sensitivity) …
puzzling properties (large photocurrents, red-shifted spectrum, and extreme light sensitivity) …
Machine learning-guided channelrhodopsin engineering enables minimally invasive optogenetics
CN Bedbrook, KK Yang, JE Robinson, ED Mackey… - Nature …, 2019 - nature.com
We engineered light-gated channelrhodopsins (ChRs) whose current strength and light
sensitivity enable minimally invasive neuronal circuit interrogation. Current ChR tools …
sensitivity enable minimally invasive neuronal circuit interrogation. Current ChR tools …
Rhodopsins at a glance
Rhodopsins are photoreceptive membrane proteins consisting of a common heptahelical
transmembrane architecture that contains a retinal chromophore. Rhodopsin was first …
transmembrane architecture that contains a retinal chromophore. Rhodopsin was first …
NeoR, a near-infrared absorbing rhodopsin
The Rhizoclosmatium globosum genome encodes three rhodopsin-guanylyl cyclases
(RGCs), which are predicted to facilitate visual orientation of the fungal zoospores. Here, we …
(RGCs), which are predicted to facilitate visual orientation of the fungal zoospores. Here, we …