Persisters refer to genetically drug susceptible quiescent (non-growing or slow growing)
bacteria that survive in stress environments such as antibiotic exposure, acidic and …

Antimicrobial resistance (AMR) and persistence are associated with an elevated risk of
treatment failure and relapsing infections. They are thus important drivers of increased …

The viable but nonculturable (VBNC) state has been recognized as a strategy for bacteria to
cope with stressful environments; in this state, bacteria fail to grow on routine culture …

Persisters represent a small subpopulation of non-or slow-growing bacterial cells that are
tolerant to killing by antibiotics. Despite their prominent role in the recalcitrance of chronic …

Protein aggregation occurs as a consequence of perturbations in protein homeostasis that
can be triggered by environmental and cellular stresses. The accumulation of protein …

Adenosine triphosphate (ATP) is a central metabolite that plays an indispensable role in
various cellular processes, from energy supply to cell‐to‐cell signaling. Nature has …

The occurrence and proliferation of antibiotic-resistance genes (ARGs)/antibiotic-resistant
bacteria (ARB) have been currently aggravating due to the increase of antibiotic residues in …

Persisters are nongrowing, transiently antibiotic-tolerant bacteria within a clonal population
of otherwise susceptible cells. Their formation is triggered by environmental cues and …

For decades, mankind has dominated the battle against bacteria, yet the tide is slowly
turning. Our antibacterial strategies are becoming less effective, allowing bacteria to get the …

Insufficient development of new antibiotics and the rising resistance of bacteria to those that
we have are putting the world at risk of losing the most widely curative class of medicines …