Nitric oxide and its production by iNOS is an established mechanism critical to tumor
promotion or suppression. Macrophages have important roles in immunity, development …

Macroautophagy (referred to here as autophagy) degrades and recycles cytoplasmic
constituents to sustain cellular and mammalian metabolism and survival during starvation …

Arginine, one among the 20 most common natural amino acids, has a pivotal role in cellular
physiology as it is being involved in numerous cellular metabolic and signaling pathways …

Highlights•Reviewed the function of arginine and its metabolites in arginine deprivation
therapy.•Discussed the difference of arginine deiminase and recombinant human arginase …

Arginine is a semi essential amino acid that is used in protein biosynthesis. It can be
obtained from daily food intake or synthesized in the body through the urea cycle using l …

Cancer is caused by uncontrollable growth of neoplastic cells, leading to invasion of
adjacent and distant tissues resulting in death. Cancer cells have specific nutrient (s) …

Glioblastoma, also referred to as glioblastoma multiforme (GBM), is grade IV astrocytoma
characterized by being fast-growing and the most aggressive brain tumor. In adults, it is the …

Simple Summary The most prevalent and lethal primary brain tumor, glioblastoma
multiforme (GBM), exhibits fast growth and widespread invasion and has a poor prognosis …

Human gut microbiota contains a large, complex, dynamic microbial community of
approximately 1014 microbes from more than 1,000 microbial species, ie, equivalent to 4× …

Ornithine transcarbamylase (OTC; EC 2.1. 3.3) is a ubiquitous enzyme found in almost all
organisms, including vertebrates, microorganisms, and plants. Anabolic, mostly trimeric …