Hydrogels are basically three-dimensional network structures which are formulated from
specific natural and synthetic polymers. They have the ability to absorb and carry sufficient …

It is well-known that aqueous dispersions of phospholipids spontaneously assemble into
bilayer structures. These structures have numerous applications across chemistry and …

From a clinical perspective, local anesthetics have rather widespread application in regional
blockade for surgery, postoperative analgesia, acute/chronic pain control, and even cancer …

Burn wound treatment remains a significant issue in wound care management especially
when multidrug resistant bacterial infection and accumulation are present. Delayed wound …

Introduction: There is a clinical need for pharmaceutical dosage forms devised to prolong
the acting time of local anesthetic (LA) agents or to reduce their toxicity. Encapsulation of LA …

Transdermal drug delivery is favored in clinical therapy because of its ability to overcome the
shortcomings of the first pass elimination of the liver caused by traditional oral administration …

Introduction: Topical anesthesia is widely used in dentistry to reduce pain caused by needle
insertion and injection of the anesthetic. However, successful anesthesia is not always …

In recent years, the development of hybrid drug delivery systems, such as hydrogels and
nanoparticles, has gained considerable attention as new formulations for skin-delivery …

Lipid nanoparticles (liposomes) were first described in 1965, and several work have led to
development of important technical advances like triggered release liposomes and drug …

A new topical delivery system based on bio polysaccharides-based hydrogels for the local
anesthetics drug benzocaine, was primed to circumvent its limited efficacy and short …