Radical oxygen species: an important breakthrough point for botanical drugs to regulate oxidative stress and treat the disorder of glycolipid metabolism

M Luo, Y Zheng, S Tang, L Gu, Y Zhu, R Ying… - Frontiers in …, 2023 - frontiersin.org
Background: The incidence of glycolipid metabolic diseases is extremely high worldwide,
which greatly hinders people's life expectancy and patients' quality of life. Oxidative stress …

Syzygium jambos L. Alston: An Insight Into its Phytochemistry, Traditional Uses, and Pharmacological Properties

MA Ochieng, W Ben Bakrim, GTM Bitchagno… - Frontiers in …, 2022 - frontiersin.org
Medicinal plants have been used since ancient times for human healthcare as drugs, spices,
and food additives. The progress in technology and medicine observed, the last decades …

[HTML][HTML] Function of selected natural antidiabetic compounds with potential against cancer via modulation of the PI3K/AKT/mTOR cascade

ADR Nurcahyanti, A Jap, J Lady, D Prismawan… - Biomedicine & …, 2021 - Elsevier
Diabetes mellitus (DM) is a metabolic disorder with growing global incidence, as 387 million
people were diagnosed in 2014 with an expected projection of 642 million in 2040. Several …

Coriander oil reverses dexamethasone-induced insulin resistance in rats

MF Mahmoud, N Ali, I Mostafa, RA Hasan, M Sobeh - Antioxidants, 2022 - mdpi.com
In the present study, we aimed to investigate the effect of coriander oil on dexamethasone-
induced insulin resistance in rats and characterize its chemical composition using gas …

n-3 PUFA deficiency aggravates streptozotocin-induced pancreatic injury in mice but dietary supplementation with DHA/EPA protects the pancreas via suppressing …

HY Zou, HJ Zhang, YC Zhao, XY Li, YM Wang… - Marine Drugs, 2023 - mdpi.com
It has been reported that dietary n-3 polyunsaturated fatty acids (n-3 PUFAs) exert
therapeutic potential for the preservation of functional β-cell mass. However, the effect of …

Cathepsin S activity controls chronic stress-induced muscle atrophy and dysfunction in mice

Y Wan, L Piao, S Xu, X Meng, Z Huang, A Inoue… - Cellular and Molecular …, 2023 - Springer
Exposure to chronic psychological stress (CPS) is an intractable risk factor for inflammatory
and metabolic diseases. Lysosomal cysteinyl cathepsins play an important role in human …

Roles of Syzygium in Anti-Cholinesterase, Anti-Diabetic, Anti-Inflammatory, and Antioxidant: From Alzheimer's Perspective

MS Amir Rawa, MKN Mazlan, R Ahmad, T Nogawa… - Plants, 2022 - mdpi.com
Alzheimer's disease (AD) causes progressive memory loss and cognitive dysfunction. It is
triggered by multifaceted burdens such as cholinergic toxicity, insulin resistance …

[Retracted] Watery Rose Apple: A Comprehensive Review of Its Traditional Uses, Nutritional Value, Phytochemistry, and Therapeutic Merits against Inflammation …

M Yassir, WB Bakrim, MF Mahmoud… - Oxidative Medicine …, 2022 - Wiley Online Library
The myrtle family, Myrtaceae, constitutes over 5500 species, and Syzygium is considered
the largest genus of the flowering plants within the family. The watery rose apple, Syzygium …

Syzygium aqueum (Burm.f.) Alston Prevents Streptozotocin-Induced Pancreatic Beta Cells Damage via the TLR-4 Signaling Pathway

MF Mahmoud, S Abdelaal, HO Mohammed… - Frontiers in …, 2021 - frontiersin.org
Although several treatments are available for the treatment of type 2 diabetes mellitus,
adverse effects and cost burden impose the search for safe, efficient, and cost-effective …

[HTML][HTML] Revisiting the nutritional and functional value and health-promoting potential of Syzygium species

ANV de Araújo, EL de Souza… - Journal of Functional …, 2024 - Elsevier
Syzygium species are consumed worldwide, and their edible conventional and
unconventional parts contain nutrients and bioactive compounds with beneficial health …