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The oral microbiome: Role of key organisms and complex networks in oral health and disease
L Sedghi, V DiMassa, A Harrington… - Periodontology …, 2021 - Wiley Online Library
States of oral health and disease reflect the compositional and functional capacities of, as
well as the interspecies interactions within, the oral microbiota. The oral cavity exists as a …
well as the interspecies interactions within, the oral microbiota. The oral cavity exists as a …
Periodontal disease: the good, the bad, and the unknown
LM Sedghi, M Bacino, YL Kapila - Frontiers in cellular and infection …, 2021 - frontiersin.org
Periodontal disease is classically characterized by progressive destruction of the soft and
hard tissues of the periodontal complex, mediated by an interplay between dysbiotic …
hard tissues of the periodontal complex, mediated by an interplay between dysbiotic …
SARS-CoV-2 infection of the oral cavity and saliva
Despite signs of infection—including taste loss, dry mouth and mucosal lesions such as
ulcerations, enanthema and macules—the involvement of the oral cavity in coronavirus …
ulcerations, enanthema and macules—the involvement of the oral cavity in coronavirus …
Human oral mucosa cell atlas reveals a stromal-neutrophil axis regulating tissue immunity
The oral mucosa remains an understudied barrier tissue. This is a site of rich exposure to
antigens and commensals, and a tissue susceptible to one of the most prevalent human …
antigens and commensals, and a tissue susceptible to one of the most prevalent human …
Neutrophil extracellular traps and extracellular histones potentiate IL-17 inflammation in periodontitis
Neutrophil infiltration is a hallmark of periodontitis, a prevalent oral inflammatory condition in
which Th17-driven mucosal inflammation leads to destruction of tooth-supporting bone …
which Th17-driven mucosal inflammation leads to destruction of tooth-supporting bone …
Current understanding of periodontal disease pathogenesis and targets for host‐modulation therapy
G Hajishengallis, T Chavakis… - Periodontology 2000, 2020 - Wiley Online Library
Recent advances indicate that periodontitis is driven by reciprocally reinforced interactions
between a dysbiotic microbiome and dysregulated inflammation. Inflammation is not only a …
between a dysbiotic microbiome and dysregulated inflammation. Inflammation is not only a …
[HTML][HTML] Periodontitis: a multifaceted disease of tooth-supporting tissues
Periodontitis is an infection-driven inflammatory disease in which the composition of biofilms
plays a significant role. Dental plaque accumulation at the gingival margin initiates an …
plays a significant role. Dental plaque accumulation at the gingival margin initiates an …
The cytokine network involved in the host immune response to periodontitis
W Pan, Q Wang, Q Chen - International journal of oral science, 2019 - nature.com
Periodontitis is an inflammatory disease involving the destruction of both soft and hard tissue
in the periodontal region. Although dysbiosis of the local microbial community initiates local …
in the periodontal region. Although dysbiosis of the local microbial community initiates local …
Polymicrobial communities in periodontal disease: Their quasi‐organismal nature and dialogue with the host
G Hajishengallis, RJ Lamont - Periodontology 2000, 2021 - Wiley Online Library
In health, indigenous polymicrobial communities at mucosal surfaces maintain an ecological
balance via both inter‐microbial and host‐microbial interactions that promote their own and …
balance via both inter‐microbial and host‐microbial interactions that promote their own and …
The role of oral bacteria in inflammatory bowel disease
Over the past two decades, the importance of the microbiota in health and disease has
become evident. Pathological changes to the oral bacterial microbiota, such as those …
become evident. Pathological changes to the oral bacterial microbiota, such as those …