Glioblastoma (GBM) is a particularly devastating tumor with a median survival of about 16
months. Recent research has revealed novel insights into the outstanding heterogeneity of …

Glioblastoma (GBM) is the most common and lethal tumor of the central nervous system. The
natural history of treated GBM remains very poor with 5-year survival rates of 5%. Survival …

Abstract Epidemiologists in the Brain Tumor Epidemiology Consortium (BTEC) have
prioritized areas for further research. Although many risk factors have been examined over …

The purpose of this review is to provide a sufficiently detailed perspective on epidemiologic
studies of primary brain tumors to encourage multidisciplinary etiologic and prognostic …

Glioblastoma multiforme (GBM) frequently involves amplification and alteration of the
epidermal growth factor receptor (EGFR) gene, resulting in overexpression of varied …

Purpose: The epidermal growth factor receptor (EGFR) is overexpressed in∼ 50% to 60% of
glioblastoma multiforme tumors, and the most common EGFR mutant, EGFRvIII, is …

We undertook a Phase I/II trial in patients with apparent recurrent glioblastoma multiforme
(GBM) based on imaging studies to determine the safety and tumor response of repetitive …

BACKGROUND No age‐adjusted or histologic‐adjusted assessments of the association
between extent of resection and risk of either recurrence or death exist for neurosurgical …

Glioblastoma multiforme (GBM) is commonly known as the most aggressive primary CNS
tumor in adults. The mean survival of it is 14 to 15 months, following the standard therapy …

Aquaporin-4 (AQP4) is a highly conserved water channel protein. In rats, AQP4 is expressed
in astrocyte foot processes and is important in brain water homeostasis. AQP4 expression …