DNA evidence sample processing typically involves DNA extraction, quantification, and STR
amplification; however, DNA loss can occur at both the DNA extraction and quantification …

Protein is a major component of all biological evidence, often the matrix that embeds other
biomolecules such as polynucleotides, lipids, carbohydrates, and small molecules. The …

Human identification from biological material is largely dependent on the ability to
characterize genetic polymorphisms in DNA. Unfortunately, DNA can degrade in the …

Mass spectrometry-based proteomics has been a useful tool for addressing numerous
questions in basic biology research for many years. This success, combined with the …

DNA profiling has emerged as the gold standard for the identification of victims in mass
disaster events providing an ability to identify victims, reassociate remains and provide …

While shed hairs are one of the most commonly encountered evidence types, they are
among the most limited in terms of DNA quantity and quality. As a result, nuclear DNA short …

Keratinous tissues such as nail, hair, horn, scales and feather have been used as a source
of DNA for over 20 years. Particular benefits of such tissues include the ease with which they …

Forensic mitochondrial DNA (mtDNA) analysis conducted using next-generation sequencing
(NGS), also known as massively parallel sequencing (MPS), as compared to Sanger-type …

DNA deposited by individuals' hands is a routine part of forensic analysis, yet little is
understood about the precise cellular contents left by handling.“Dead” skin cells known as …

Age prediction is of great importance for criminal investigation and judicial expertise. DNA
methylation status is considered a promising method to infer tissue age by virtue of age …