Defensins: Transcriptional regulation and function beyond antimicrobial activity

G Contreras, I Shirdel, MS Braun, M Wink - Developmental & Comparative …, 2020 - Elsevier
Defensins are one the largest group of antimicrobial peptides and are part of the innate
defence. Defensins are produced by animals, plants and fungi. In animals and plants …

Learning to starve: impacts of food limitation beyond the stress period

MD McCue, JS Terblanche… - Journal of Experimental …, 2017 - journals.biologists.com
Starvation is common among wild animal populations, and many individuals experience
repeated bouts of starvation over the course of their lives. Although much information has …

Genetic constraints, transcriptome plasticity, and the evolutionary response to climate change

ML Logan, CL Cox - Frontiers in Genetics, 2020 - frontiersin.org
In situ adaptation to climate change will be critical for the persistence of many ectotherm
species due to their relative lack of dispersal capacity. Climate change is causing increases …

The tardigrade Hypsibius exemplaris dramatically upregulates DNA repair pathway genes in response to ionizing radiation

CM Clark-Hachtel, JD Hibshman, T De Buysscher… - Current Biology, 2024 - cell.com
Tardigrades can survive remarkable doses of ionizing radiation, up to about 1,000 times the
lethal dose for humans. How they do so is incompletely understood. We found that the …

Wolbachia enhances the survival of Drosophila infected with fungal pathogens

JI Perlmutter, A Atadurdyyeva, ME Schedl, RL Unckless - BMC biology, 2025 - Springer
Background Wolbachia bacteria of arthropods are at the forefront of basic and translational
research on multipartite host-symbiont-pathogen interactions. These vertically transmitted …

Predictive features of gene expression variation reveal mechanistic link with differential expression

OM Sigalova, A Shaeiri, M Forneris… - Molecular systems …, 2020 - embopress.org
For most biological processes, organisms must respond to extrinsic cues, while maintaining
essential gene expression programmes. Although studied extensively in single cells, it is still …

The genomewide transcriptional response underlying the pea aphid wing polyphenism

NN Vellichirammal, N Madayiputhiya… - Molecular …, 2016 - Wiley Online Library
Phenotypic plasticity is a key life history strategy used by many plants and animals living in
heterogeneous environments. A multitude of studies have investigated the costs and limits of …

[HTML][HTML] Insulin signalling elicits hunger-induced feeding in Drosophila

SR Sudhakar, H Pathak, N Rehman, J Fernandes… - Developmental …, 2020 - Elsevier
Insulin, a highly conserved peptide hormone, links nutrient availability to metabolism and
growth in animals. In fed states insulin levels remain high and in animals that are food …

Transcriptome Sequencing Reveals Large-Scale Changes in Axenic Aedes aegypti Larvae

KJ Vogel, L Valzania, KL Coon… - PLoS neglected …, 2017 - journals.plos.org
Mosquitoes host communities of microbes in their digestive tract that consist primarily of
bacteria. We previously reported that Aedes aegypti larvae colonized by a native community …

Deletions of the cystathionine-β-synthase (CBS) and cystathionine-γ-lyase (CSE) genes, involved in the control of hydrogen sulfide biosynthesis, significantly affect …

MV Shaposhnikov, AS Zakluta, NV Zemskaya… - Mechanisms of ageing …, 2022 - Elsevier
The gasotransmitter hydrogen sulfide (H 2 S) is an important biological mediator, playing an
essential role in many physiological and pathological processes. It is produced by …