Chronic pain is a maladaptive neurological disease that remains a major health problem. A
deepening of our knowledge on mechanisms that cause pain is a prerequisite to develo** …

Increasing evidence indicates that the brain regulates peripheral immunity, yet whether and
how the brain represents the state of the immune system remains unclear. Here, we show …

This systematic review aimed to evaluate the potential anti-inflammatory effect of
Rosmarinus officinalis in preclinical in vivo models of inflammation. A search was conducted …

Inflammation generally leads to recruitment of monocyte-derived macrophages. What
regulates the fate of these cells and to what extent they can assume the identity and function …

Biologically produced reactive oxygen species (ROS) are important signaling molecules in
the human body. Despite their importance under normal conditions, abnormal …

Mitochondrial dysfunction is linked to age-associated inflammation or inflammaging, but
underlying mechanisms are not understood. Analyses of 700 human blood transcriptomes …

Homeostasis of the cellular redox status plays an indispensable role in diverse physiological
and pathological processes. Hypochlorite anion (ClO–) and glutathione (GSH) represent an …

Chronic, low-grade inflammation triggered by excess intake of dietary lipids has been
proposed to contribute to the pathogenesis of metabolic disorders, such as obesity, insulin …

Bone healing involves complex processes including inflammation, induction, and
remodeling. In this context, anti-inflammatory and osteoconductive multi-functional …

The CCL20/CCR6 axis is implicated in the migration of CCR6+ immune cells towards
CCL20, its sole ligand, whose expression is increased during inflammatory processes and is …