There are well-established disparities in cancer incidence and outcomes by race/ethnicity
that result from the interplay between structural, socioeconomic, socio-environmental …

Triple-negative breast cancer (TNBC) is an aggressive subset of breast carcinomas that lack
expression of estrogen receptor (ER), progesterone receptor (PR), and human epidermal …

The prevalence and spectrum of germline mutations in BRCA1 and BRCA2 have been
reported in single populations, with the majority of reports focused on White in Europe and …

Triple negative breast cancer (TNBC) is a heterogeneous disease with aggressive behavior
and poor prognosis. Genomic sequencing has detected a distinctive mutational portrait of …

Abstract Background: Sub-Saharan Africa (SSA) has a high proportion of premenopausal
hormone receptor negative breast cancer. Previous studies reported a strikingly high …

Background Identification of BRCA mutations in breast cancer (BC) patients influences
treatment and survival and may be of importance for their relatives. Testing is often restricted …

Background Breast cancer (BC) is the most common cancer and related cause of mortality
among Hispanics, yet susceptibility has been understudied. BRCA1 and BRCA2 (BRCA) …

Hereditary cancer predisposition gene testing allows the identification of individuals at high
risk of cancer that may benefit from increased surveillance, chemoprevention, and …

Objective We sought to characterize referral patterns for genetic counseling for women with
ovarian cancer and hypothesized that differences in referral and testing rates are shaped by …

Purpose Platinum plays an important role in the treatment of triple-negative breast cancer
(TNBC) in neoadjuvant and metastatic settings. However, its role in an adjuvant setting …