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Candida albicans cell-type switching and functional plasticity in the mammalian host
SM Noble, BA Gianetti, JN Witchley - Nature Reviews Microbiology, 2017 - nature.com
Candida albicans is a ubiquitous commensal of the mammalian microbiome and the most
prevalent fungal pathogen of humans. A cell-type transition between yeast and hyphal …
prevalent fungal pathogen of humans. A cell-type transition between yeast and hyphal …
Candida albicans Antifungal Resistance and Tolerance in Bloodstream Infections: The Triad Yeast-Host-Antifungal
S Costa-de-Oliveira, AG Rodrigues - Microorganisms, 2020 - mdpi.com
Candida albicans represents the most frequent isolated yeast from bloodstream infections.
Despite the remarkable progress in diagnostic and therapeutic approaches, these infections …
Despite the remarkable progress in diagnostic and therapeutic approaches, these infections …
Candida Infections of the Genitourinary Tract
JM Achkar, BC Fries - Clinical microbiology reviews, 2010 - journals.asm.org
All humans are colonized with Candida species, mostly Candida albicans, yet some develop
diseases due to Candida, among which genitourinary manifestations are extremely …
diseases due to Candida, among which genitourinary manifestations are extremely …
Genetic and phenotypic intra-species variation in Candida albicans
Candida albicans is a commensal fungus of the human gastrointestinal tract and a prevalent
opportunistic pathogen. To examine diversity within this species, extensive genomic and …
opportunistic pathogen. To examine diversity within this species, extensive genomic and …
Passage through the mammalian gut triggers a phenotypic switch that promotes Candida albicans commensalism
K Pande, C Chen, SM Noble - Nature genetics, 2013 - nature.com
Abstract Among∼ 5,000,000 fungal species, C. albicans is exceptional in its lifelong
association with humans, either within the gastrointestinal microbiome or as an invasive …
association with humans, either within the gastrointestinal microbiome or as an invasive …
Gene flow contributes to diversification of the major fungal pathogen Candida albicans
J Ropars, C Maufrais, D Diogo… - Nature …, 2018 - nature.com
Elucidating population structure and levels of genetic diversity and recombination is
necessary to understand the evolution and adaptation of species. Candida albicans is the …
necessary to understand the evolution and adaptation of species. Candida albicans is the …
Genomic plasticity of the human fungal pathogen Candida albicans
The genomic plasticity of Candida albicans, a commensal and common opportunistic fungal
pathogen, continues to reveal unexpected surprises. Once thought to be asexual, we now …
pathogen, continues to reveal unexpected surprises. Once thought to be asexual, we now …
Genotypic Evolution of Azole Resistance Mechanisms in Sequential Candida albicans Isolates
ABSTRACT TAC1 (for transcriptional activator of CDR genes) is critical for the upregulation
of the ABC transporters CDR1 and CDR2, which mediate azole resistance in Candida …
of the ABC transporters CDR1 and CDR2, which mediate azole resistance in Candida …
Molecular Phylogenetics of Candida albicans
FC Odds, ME Bougnoux, DJ Shaw, JM Bain… - Eukaryotic …, 2007 - journals.asm.org
We analyzed data on multilocus sequence ty** (MLST), ABC ty**, mating type-like locus
(MAT) status, and antifungal susceptibility for a panel of 1,391 Candida albicans isolates …
(MAT) status, and antifungal susceptibility for a panel of 1,391 Candida albicans isolates …
Systematic Phenoty** of a Large-Scale Candida glabrata Deletion Collection Reveals Novel Antifungal Tolerance Genes
T Schwarzmueller, B Ma, E Hiller, F Istel… - PLoS …, 2014 - journals.plos.org
The opportunistic fungal pathogen Candida glabrata is a frequent cause of candidiasis,
causing infections ranging from superficial to life-threatening disseminated disease. The …
causing infections ranging from superficial to life-threatening disseminated disease. The …