Fabrication of a coculture organoid model in the biomimetic matrix of alginate to investigate breast cancer progression in a TAMs-leading immune microenvironment

NY Xu, J Li, ML Wang, XY Chen, R Tang… - ACS Applied Materials …, 2024 - ACS Publications
The current research models of breast cancer are usually limited in their capacity to
recapitulate the tumor microenvironment in vitro. The lack of an extracellular matrix (ECM) …

ELK4-mediated lncRNA SNHG22 promotes gastric cancer progression through interacting with EZH2 and regulating miR-200c-3p/Notch1 axis

X Mao, T Ji, A Liu, Y Weng - Cell death & disease, 2021 - nature.com
Long non-coding RNAs (lncRNAs) play important regulatory roles in the initiation and
progression of various cancers. However, the biological roles and the potential mechanisms …

The LAMB3-EGFR signaling pathway mediates synergistic Anti-Cancer effects of berberine and emodin in Pancreatic cancer

C Xu, S Pascual-Sabater, C Fillat, A Goel - Biochemical Pharmacology, 2024 - Elsevier
Pancreatic ductal adenocarcinoma (PDAC) is a lethal malignancy, primarily due to the
intrinsic development of chemoresistance. The most apparent histopathological feature …

[HTML][HTML] S100A10 promotes pancreatic ductal adenocarcinoma cells proliferation, migration and adhesion through JNK/LAMB3-LAMC2 axis

H Lin, P Yang, B Li, Y Chang, Y Chen, Y Li, K Liu… - Cancers, 2022 - mdpi.com
Simple Summary Despite the advance in therapeutic strategy, the prognosis of pancreatic
ductal adenocarcinoma (PDAC) is still unsatisfactory, with a 5-year survival rate of less than …