The phylogenomics of evolving virus virulence
How virulence evolves after a virus jumps to a new host species is central to disease
emergence. Our current understanding of virulence evolution is based on insights drawn …
emergence. Our current understanding of virulence evolution is based on insights drawn …
Evolution in the light of fitness landscape theory
By formalizing the relationship between genotype or phenotype and fitness, fitness
landscapes harbor information on molecular and evolutionary constraints. The shape of the …
landscapes harbor information on molecular and evolutionary constraints. The shape of the …
Neural networks enable efficient and accurate simulation-based inference of evolutionary parameters from adaptation dynamics
The rate of adaptive evolution depends on the rate at which beneficial mutations are
introduced into a population and the fitness effects of those mutations. The rate of beneficial …
introduced into a population and the fitness effects of those mutations. The rate of beneficial …
Next-generation cophylogeny: unravelling eco-evolutionary processes
A fundamental question in evolutionary biology is how microevolutionary processes
translate into species diversification. Cophylogeny provides an appropriate framework to …
translate into species diversification. Cophylogeny provides an appropriate framework to …
Towards an integrative view of virus phenotypes
Understanding how phenotypes emerge from genotypes is a foundational goal in biology.
As challenging as this task is when considering cellular life, it is further complicated in the …
As challenging as this task is when considering cellular life, it is further complicated in the …
Measuring coevolutionary dynamics in species-rich communities
Identifying different types of coevolutionary dynamics is important for understanding
biodiversity and infectious disease. Past work has often focused on pairs of interacting …
biodiversity and infectious disease. Past work has often focused on pairs of interacting …
Functional comparison of MERS-coronavirus lineages reveals increased replicative fitness of the recombinant lineage 5
S Schroeder, C Mache, H Kleine-Weber… - Nature …, 2021 - nature.com
Middle East respiratory syndrome coronavirus (MERS-CoV) is enzootic in dromedary
camels across the Middle East and Africa. Virus-induced pneumonia in humans results from …
camels across the Middle East and Africa. Virus-induced pneumonia in humans results from …
Construction and characterization of synthetic bacterial community for experimental ecology and evolution
Experimental microbial ecology and evolution have yielded foundational insights into
ecological and evolutionary processes using simple microcosm setups and phenotypic …
ecological and evolutionary processes using simple microcosm setups and phenotypic …
Novel genomic approaches to study antagonistic coevolution between hosts and parasites
Host‐parasite coevolution is ubiquitous, sha** genetic and phenotypic diversity and the
evolutionary trajectory of interacting species. With the advances of high throughput …
evolutionary trajectory of interacting species. With the advances of high throughput …
Ecological and evolutionary processes sha** viral genetic diversity
The contemporary genomic diversity of viruses is a result of the continuous and dynamic
interaction of past ecological and evolutionary processes. Thus, genome sequences of …
interaction of past ecological and evolutionary processes. Thus, genome sequences of …