Selenocysteine (Sec), the 21st amino acid, exists naturally in all kingdoms of life as the
defining entity of selenoproteins. Sec is a cysteine (Cys) residue analogue with a selenium …

The examination of house dust mite extracts has indicated that over 30 different proteins can
induce IgE antibody in patients allergic to the house dust mite. There are however dominant …

Since the discovery of immunoglobulin E (IgE) as a mediator of allergic diseases in 1967,
our knowledge about the immunological mechanisms of IgE‐mediated allergies has …

The availability of allergen molecules ('components') from several protein families has
advanced our understanding of immunoglobulin E (IgE)‐mediated responses and enabled …

Background The evolution of the IgE response to the numerous allergen molecules of
Dermatophagoides pteronyssinus is still unknown. Objectives We sought to characterize the …

The association between house dust allergy and asthma has long been recognized, and it
has been demonstrated that a major allergen in house dust is related to the presence of …

The role of mites of the family Pyroglyphidae as the single most important source of house
dust allergens was established 20 years ago.'Since that time, evidence for sensitization of …

Conservatively, at least 100 million people are affected by house dust mite allergy
worldwide, manifesting itself as asthma, rhinitis or atopic dermatitis. Despite the growing …

The house dust mite (HDM) Dermatophagoides pteronyssinus is one of most important
allergen sources and a major elicitor of allergic asthma. We screened a D. pteronyssinus …

Immunoglobulin E (IgE; see ref. 1) has a central role in allergic reactions although it rarely
exceeds 5 µg ml− 1 even in the serum of severely allergic individuals. Both mast cells and …