Despite tremendous successes in the field of antibiotic discovery seen in the previous
century, infectious diseases have remained a leading cause of death. More specifically …

Lipopolysaccharide molecules represent a unique family of glycolipids based on a highly
conserved lipid moiety known as lipid A. These molecules are produced by most gram …

Following their initial discovery in the 1940s, polymyxin antibiotics fell into disfavor due to
their potential clinical toxicity, especially nephrotoxicity. However, the dry antibiotic …

The global incidence of drug-resistant Gram-negative bacillary infections has been
increasing, and there is a dire need to develop novel strategies to overcome this problem …

Glucose arguably is the most important energy carrier, carbon source for metabolites and
building block for biopolymers in all kingdoms of life. The proper function of animal organs …

Introduction to Proteins provides a comprehensive and state-of-the-art introduction to the
structure, function, and motion of proteins for students, faculty, and researchers at all levels …

l-Carnitine is an amino acid derivative widely known for its involvement in the transport of
long-chain fatty acids into the mitochondrial matrix, where fatty acid oxidation occurs …

Amyloid β (Aβ) ion channels destabilize cellular ionic homeostasis, which contributes to
neurotoxicity in Alzheimer's disease. The relative roles of various Aβ isoforms are poorly …

The carnitine/acylcarnitine carrier (CAC) is a transport protein of the inner mitochondrial
membrane that belongs to the mitochondrial carrier protein family. In its cytosolic …

Outer membrane β-barrel proteins (OMPs) are crucial for numerous cellular processes in
prokaryotes and eukaryotes. Despite extensive studies on OMP biogenesis, it is unclear why …