Retrieving, analyzing, and processing large data can be challenging. An effective and
efficient mechanism for overcoming these challenges is to cluster the data into a compact …

Evaluating whether an intervention works when trialled in groups of individuals can pose
complex challenges for clinical research. Cluster randomised controlled trials involve the …

Background Chlorhexidine skin antisepsis is frequently recommended for most surgical
procedures; however, it is unclear if these recommendations should apply to surgery …

The delivery of comprehensive sexuality education to adolescents at school is recognized
as a long-term strategy to support adolescent health. Suboptimal sexual and reproductive …

Background HIV-TB treatment integration reduces mortality. Operational implementation of
integrated services is challenging. This study assessed the impact of quality improvement …

Cluster randomized controlled trials (cRCTs) are commonly used by clinical researchers.
The advantages of cRCTs include preventing treatment contamination, enhancing …

Objective To evaluate the impact of Teach-Back on communication quality in a national
telephone-based telehealth service, for callers varying in health literacy. Design Cross …

Objectives To investigate the extent to which cluster sizes vary in stepped-wedge cluster
randomised trials (SW-CRT) and whether any variability is accounted for during the sample …

In a cluster-randomized trial (CRT), the number of participants enrolled often varies across
clusters. This variation should be considered during both trial design and data analysis to …

Background The current methodology for sample size calculations for stepped-wedge
cluster randomised trials (SW-CRTs) is based on the assumption of equal cluster sizes …