Enhancing the therapeutic efficacy of nanoparticles for cancer treatment using versatile targeted strategies

H Tian, T Zhang, S Qin, Z Huang, L Zhou, J Shi… - Journal of hematology & …, 2022 - Springer
Poor targeting of therapeutics leading to severe adverse effects on normal tissues is
considered one of the obstacles in cancer therapy. To help overcome this, nanoscale drug …

Ultrasound-based micro-/nanosystems for biomedical applications

H Huang, Y Zheng, M Chang, J Song, L **a… - Chemical …, 2024 - ACS Publications
Due to the intrinsic non-invasive nature, cost-effectiveness, high safety, and real-time
capabilities, besides diagnostic imaging, ultrasound as a typical mechanical wave has been …

Advanced biotechnology-assisted precise sonodynamic therapy

Y Zhang, X Zhang, H Yang, L Yu, Y Xu… - Chemical Society …, 2021 - pubs.rsc.org
Despite significant advances, the therapeutic impact of photodynamic therapy is still
substantially hampered by the restricted penetration depth of light and the reactive oxygen …

Stimuli‐responsive nanoparticles for controlled drug delivery in synergistic cancer immunotherapy

J Zhang, Y Lin, Z Lin, Q Wei, J Qian, R Ruan… - Advanced …, 2022 - Wiley Online Library
Cancer immunotherapy has achieved promising clinical progress over the recent years for
its potential to treat metastatic tumors and inhibit their recurrences effectively. However, low …

Cancer cell membrane-coated C-TiO2 hollow nanoshells for combined sonodynamic and hypoxia-activated chemotherapy

S Ning, X Dai, W Tang, Q Guo, M Lyu, D Zhu, W Zhang… - Acta biomaterialia, 2022 - Elsevier
Sonodynamic therapy (SDT) is a promising strategy for tumor treatment that satisfies all
requirements of penetrating deep-seated tissues without causing additional trauma …

Theranostic fluorescent probes

A Sharma, P Verwilst, M Li, D Ma, N Singh… - Chemical …, 2024 - ACS Publications
The ability to gain spatiotemporal information, and in some cases achieve spatiotemporal
control, in the context of drug delivery makes theranostic fluorescent probes an attractive …

Tumor microenvironment-responsive manganese-based nanomaterials for cancer treatment

H Fan, Z Guo - Coordination Chemistry Reviews, 2023 - Elsevier
Tumor microenvironment (TME), which characteristically displays hypoxia,
immunosuppression, reprogramming metabolism and mild acidity, has been considered as …

Stimuli responsive nanosonosensitizers for sonodynamic therapy

Z Jiang, W **ao, Q Fu - Journal of Controlled Release, 2023 - Elsevier
Sonodynamic therapy (SDT) has gained significant attention in the treatment of deep tumors
and multidrug-resistant (MDR) bacterial infections due to its high tissue penetration depth …

Reactive oxygen species-upregulating nanomedicines towards enhanced cancer therapy

Y Ding, Q Pan, W Gao, Y Pu, K Luo, B He - Biomaterials Science, 2023 - pubs.rsc.org
Reactive oxygen species (ROS) play a crucial role in physiological and pathological
processes, emerging as a therapeutic target in cancer. Owing to the high concentration of …

Ultrasound‐activated probiotics vesicles coating for titanium implant infections through bacterial cuproptosis‐like death and immunoregulation

S Li, Y Yue, W Wang, M Han, X Wan, Q Li… - Advanced …, 2024 - Wiley Online Library
Implant‐associated infections (IAIs) are the main cause of prosthetic implant failure.
Bacterial biofilms prevent antibiotic penetration, and the unique metabolic conditions in …