Cutting-edge technologies for inflamed joints on chip: how close are we?

E Kahraman, R Ribeiro, M Lamghari… - Frontiers in …, 2022 - frontiersin.org
Osteoarthritis (OA) is a painful and disabling musculoskeletal disorder, with a large impact
on the global population, resulting in several limitations on daily activities. In OA …

Impact of hydrogel stiffness on differentiation of human adipose-derived stem cell microspheroids

S Žigon-Branc, M Markovic, J Van Hoorick… - … Engineering Part A, 2019 - liebertpub.com
Hydrogels represent an attractive material platform for realization of three-dimensional (3D)
tissue-engineered constructs, as they have tunable mechanical properties, are compatible …

Development of a biomimetic arch-like 3D bioprinted construct for cartilage regeneration using gelatin methacryloyl and silk fibroin-gelatin bioinks

J Chakraborty, J Fernández-Pérez… - …, 2023 - iopscience.iop.org
In recent years, engineering biomimetic cellular microenvironments have been a top priority
for regenerative medicine. Collagen II, which is arranged in arches, forms the predominant …

Induction of articular chondrogenesis by chitosan/hyaluronic-acid-based biomimetic matrices using human adipose-derived stem cells

Y Huang, D Seitz, F König, PE Müller… - International journal of …, 2019 - mdpi.com
Cartilage repair using tissue engineering is the most advanced clinical application in
regenerative medicine, yet available solutions remain unsuccessful in reconstructing native …

[HTML][HTML] Comparison of random and aligned PCL nanofibrous electrospun scaffolds on cardiomyocyte differentiation of human adipose-derived stem cells

R Safaeijavan, M Soleimani, A Divsalar… - Iranian journal of …, 2014 - ncbi.nlm.nih.gov
Objective (s): Cardiomyocytes have small potentials for renovation and proliferation in adult
life. The most challenging goal in the field of cardiovascular tissue engineering is the …

Utility of direct 3D co-culture model for chondrogenic differentiation of mesenchymal stem cells on hyaluronan scaffold (Hyaff-11)

I Deszcz, A Lis-Nawara, P Grelewski… - Regenerative …, 2020 - academic.oup.com
This study presents direct 2D and 3D co-culture model of mesenchymal stem cells (MSCs)
line with chondrocytes isolated from patients with osteoarthritis (unaffected area). MSCs …

Does the harvesting technique affect the properties of adipose‐derived stem cells?—the comparative biological characterization

A Bajek, N Gurtowska, J Olkowska… - Journal of cellular …, 2017 - Wiley Online Library
The objective of this study was to evaluate complex biological properties of human stem
cells isolated from adipose tissue (ASCs) harvested utilizing different methods: surgical …

Differentiation of stem cells into chondrocytes and their potential clinical application in cartilage regeneration

J Cieśla, M Tomsia - Histochemistry and Cell Biology, 2025 - Springer
Cartilage diseases and injuries are considered difficult to treat owing to the low regenerative
capacity of this tissue. Using stem cells (SCs) is one of the potential methods of treating …

[HTML][HTML] The effect of high frequency electric field on enhancement of chondrogenesis in human adipose-derived stem cells

E Esfandiari, S Roshankhah, M Mardani… - Iranian journal of …, 2014 - ncbi.nlm.nih.gov
Objective (s): Osteoarthritis (OA) is globally one of the most common diseases from the
middle age onwards. Cartilage is an avascular tissue therefore it cannot be repaired in the …

Evaluation of the ability of natural and synthetic scaffolds in providing an appropriate environment for growth and chondrogenic differentiation of adipose-derived …

M Sheykhhasan, RT Qomi, N Kalhor… - Indian journal of …, 2015 - Springer
Background Although progenitor cells have been observed in articular cartilage, this part
has a limited ability to repair due to a lack of blood supply. Formerly, tissue engineering was …