Integrating machine learning and multiscale modeling—perspectives, challenges, and opportunities in the biological, biomedical, and behavioral sciences
Fueled by breakthrough technology developments, the biological, biomedical, and
behavioral sciences are now collecting more data than ever before. There is a critical need …
behavioral sciences are now collecting more data than ever before. There is a critical need …
Multiscale modeling meets machine learning: What can we learn?
Abstract Machine learning is increasingly recognized as a promising technology in the
biological, biomedical, and behavioral sciences. There can be no argument that this …
biological, biomedical, and behavioral sciences. There can be no argument that this …
Brian 2, an intuitive and efficient neural simulator
Brian 2 allows scientists to simply and efficiently simulate spiking neural network models.
These models can feature novel dynamical equations, their interactions with the …
These models can feature novel dynamical equations, their interactions with the …
NetPyNE, a tool for data-driven multiscale modeling of brain circuits
Biophysical modeling of neuronal networks helps to integrate and interpret rapidly growing
and disparate experimental datasets at multiple scales. The NetPyNE tool (www. netpyne …
and disparate experimental datasets at multiple scales. The NetPyNE tool (www. netpyne …
[HTML][HTML] Open source brain: a collaborative resource for visualizing, analyzing, simulating, and develo** standardized models of neurons and circuits
Computational models are powerful tools for exploring the properties of complex biological
systems. In neuroscience, data-driven models of neural circuits that span multiple scales are …
systems. In neuroscience, data-driven models of neural circuits that span multiple scales are …
Data-driven multiscale model of macaque auditory thalamocortical circuits reproduces in vivo dynamics
We developed a detailed model of macaque auditory thalamocortical circuits, including
primary auditory cortex (A1), medial geniculate body (MGB), and thalamic reticular nucleus …
primary auditory cortex (A1), medial geniculate body (MGB), and thalamic reticular nucleus …
Optimum trajectory learning in musculoskeletal systems with model predictive control and deep reinforcement learning
From the computational point of view, musculoskeletal control is the problem of controlling
high degrees of freedom and dynamic multi-body system that is driven by redundant muscle …
high degrees of freedom and dynamic multi-body system that is driven by redundant muscle …
Multiscale computer model of the spinal dorsal horn reveals changes in network processing associated with chronic pain
Pain-related sensory input is processed in the spinal dorsal horn (SDH) before being
relayed to the brain. That processing profoundly influences whether stimuli are correctly or …
relayed to the brain. That processing profoundly influences whether stimuli are correctly or …
Exploring the integration of informed machine learning in engineering applications: A comprehensive review
Abstract Integrating Artificial Intelligence (AI) and Machine Learning (ML) into mechanical
engineering catalyzes a transformative shift within Industry 4.0, offering unprecedented …
engineering catalyzes a transformative shift within Industry 4.0, offering unprecedented …
Synaptic and circuit mechanisms prevent detrimentally precise correlation in the develo** mammalian visual system
RA Tikidji-Hamburyan, G Govindaiah, W Guido… - Elife, 2023 - elifesciences.org
The develo** visual thalamus and cortex extract positional information encoded in the
correlated activity of retinal ganglion cells by synaptic plasticity, allowing for the refinement …
correlated activity of retinal ganglion cells by synaptic plasticity, allowing for the refinement …