Multiscale modeling meets machine learning: What can we learn?

GCY Peng, M Alber, A Buganza Tepole… - … Methods in Engineering, 2021 - Springer
Abstract Machine learning is increasingly recognized as a promising technology in the
biological, biomedical, and behavioral sciences. There can be no argument that this …

Brian 2, an intuitive and efficient neural simulator

M Stimberg, R Brette, DFM Goodman - elife, 2019 - elifesciences.org
Brian 2 allows scientists to simply and efficiently simulate spiking neural network models.
These models can feature novel dynamical equations, their interactions with the …

NetPyNE, a tool for data-driven multiscale modeling of brain circuits

S Dura-Bernal, BA Suter, P Gleeson, M Cantarelli… - Elife, 2019 - elifesciences.org
Biophysical modeling of neuronal networks helps to integrate and interpret rapidly growing
and disparate experimental datasets at multiple scales. The NetPyNE tool (www. netpyne …

[HTML][HTML] Open source brain: a collaborative resource for visualizing, analyzing, simulating, and develo** standardized models of neurons and circuits

P Gleeson, M Cantarelli, B Marin, A Quintana… - Neuron, 2019 - cell.com
Computational models are powerful tools for exploring the properties of complex biological
systems. In neuroscience, data-driven models of neural circuits that span multiple scales are …

Data-driven multiscale model of macaque auditory thalamocortical circuits reproduces in vivo dynamics

S Dura-Bernal, EY Griffith, A Barczak, MN O'Connell… - Cell reports, 2023 - cell.com
We developed a detailed model of macaque auditory thalamocortical circuits, including
primary auditory cortex (A1), medial geniculate body (MGB), and thalamic reticular nucleus …

Optimum trajectory learning in musculoskeletal systems with model predictive control and deep reinforcement learning

B Denizdurduran, H Markram, MO Gewaltig - Biological cybernetics, 2022 - Springer
From the computational point of view, musculoskeletal control is the problem of controlling
high degrees of freedom and dynamic multi-body system that is driven by redundant muscle …

Multiscale computer model of the spinal dorsal horn reveals changes in network processing associated with chronic pain

L Medlock, K Sekiguchi, S Hong… - Journal of …, 2022 - Soc Neuroscience
Pain-related sensory input is processed in the spinal dorsal horn (SDH) before being
relayed to the brain. That processing profoundly influences whether stimuli are correctly or …

Exploring the integration of informed machine learning in engineering applications: A comprehensive review

MA Bappy, M Ahmed, MA Rauf - Manam and Rauf, Md Abdur …, 2024 - papers.ssrn.com
Abstract Integrating Artificial Intelligence (AI) and Machine Learning (ML) into mechanical
engineering catalyzes a transformative shift within Industry 4.0, offering unprecedented …

Synaptic and circuit mechanisms prevent detrimentally precise correlation in the develo** mammalian visual system

RA Tikidji-Hamburyan, G Govindaiah, W Guido… - Elife, 2023 - elifesciences.org
The develo** visual thalamus and cortex extract positional information encoded in the
correlated activity of retinal ganglion cells by synaptic plasticity, allowing for the refinement …