Extracellular vesicles in liquid biopsies as biomarkers for solid tumors

B Irmer, S Chandrabalan, L Maas, A Bleckmann… - Cancers, 2023 - mdpi.com
Simple Summary During the past decade, liquid biopsy-related publications have increased
exponentially, demonstrating the great potential of screening body fluids for diagnosis …

Biological functions and current advances in isolation and detection strategies for exosome nanovesicles

K Boriachek, MN Islam, A Möller, C Salomon… - Small, 2018 - Wiley Online Library
Abstract Exosomes are nanoscale (≈ 30–150 nm) extracellular vesicles of endocytic origin
that are shed by most types of cells and circulate in bodily fluids. Exosomes carry a specific …

Enhanced therapeutic effects of mesenchymal stem cell-derived exosomes with an injectable hydrogel for hindlimb ischemia treatment

K Zhang, X Zhao, X Chen, Y Wei, W Du… - … applied materials & …, 2018 - ACS Publications
Mesenchymal stem cell (MSC)-derived exosomes have been recognized as new candidates
for cell-free treatment of various diseases. However, maintaining the retention and stability of …

Tetraspanins, more than markers of extracellular vesicles in reproduction

J Jankovičová, P Sečová, K Michalková… - International Journal of …, 2020 - mdpi.com
The participation of extracellular vesicles in many cellular processes, including reproduction,
is unquestionable. Although currently, the tetraspanin proteins found in extracellular vesicles …

Preservation and storage stability of extracellular vesicles for therapeutic applications

A Jeyaram, SM Jay - The AAPS journal, 2018 - Springer
Abstract Recently, extracellular vesicles (EVs)—including exosomes, microvesicles, and
others—have attracted interest as cell-derived biotherapeutics and drug delivery vehicles for …

[HTML][HTML] Exosomes as drug carriers for cancer therapy and challenges regarding exosome uptake

X Zhao, D Wu, X Ma, J Wang, W Hou… - Biomedicine & …, 2020 - Elsevier
With the development of biomedicine, exosomes are rapidly develo** as a new therapy
for tumors. As biological carriers, exosomes possess biological activity and can transport …

Unlocking the power of exosomes for crossing biological barriers in drug delivery

RO Elliott, M He - Pharmaceutics, 2021 - mdpi.com
Since the 2013 Nobel Prize was awarded for the discovery of vesicle trafficking, a subgroup
of nanovesicles called exosomes has been driving the research field to a new regime for …

Pathogenesis of preterm birth: bidirectional inflammation in mother and fetus

ES Green, PC Arck - Seminars in immunopathology, 2020 - Springer
Abstract Preterm birth (PTB) complicates 5–18% of pregnancies globally and is a leading
cause of maternal and fetal morbidity and mortality. Most PTB is spontaneous and idiopathic …

[HTML][HTML] Extracellular vesicles in blood: sources, effects, and applications

A Alberro, L Iparraguirre, A Fernandes… - International Journal of …, 2021 - mdpi.com
Extracellular vesicles (EVs) are important players for intercellular communication. EVs are
secreted by almost all cell types; they can transfer information between nearby or distant …

Extracellular vesicles and their engineering strategies, delivery systems, and biomedical applications

C Yang, Y Xue, Y Duan, C Mao, M Wan - Journal of Controlled Release, 2024 - Elsevier
Extracellular vesicles are nanoscale vesicles that can be secreted by all cell types, are
intracellular in origin and have the same composition as their parent cells, play a key role in …