Neurobehavioural comorbidities of epilepsy: towards a network-based precision taxonomy

BP Hermann, AF Struck, RM Busch, A Reyes… - Nature Reviews …, 2021 - nature.com
Cognitive and behavioural comorbidities are prevalent in childhood and adult epilepsies
and impose a substantial human and economic burden. Over the past century, the classic …

Clinical and experimental insight into pathophysiology, comorbidity and therapy of absence seizures

V Crunelli, ML Lőrincz, C McCafferty, RC Lambert… - Brain, 2020 - academic.oup.com
Absence seizures in children and teenagers are generally considered relatively benign
because of their non-convulsive nature and the large incidence of remittance in early …

Functional and structural brain networks in epilepsy: what have we learned?

E van Diessen, SJH Diederen, KPJ Braun… - …, 2013 - Wiley Online Library
Brain functioning is increasingly seen as a complex interplay of dynamic neural systems that
rely on the integrity of structural and functional networks. Recent studies that have …

Large scale brain models of epilepsy: dynamics meets connectomics

MP Richardson - Journal of Neurology, Neurosurgery & Psychiatry, 2012 - jnnp.bmj.com
The brain is in a constant state of dynamic change, for example switching between cognitive
and behavioural tasks, and between wakefulness and sleep. The brains of people with …

Network connectivity in epilepsy: resting state fMRI and EEG–fMRI contributions

M Centeno, DW Carmichael - Frontiers in neurology, 2014 - frontiersin.org
There is a growing body of evidence pointing toward large-scale networks underlying the
core phenomena in epilepsy, from seizure generation to cognitive dysfunction or response …

Resting-state EEG source localization and functional connectivity in schizophrenia-like psychosis of epilepsy

L Canuet, R Ishii, RD Pascual-Marqui, M Iwase… - PloS one, 2011 - journals.plos.org
Background It is unclear whether, like in schizophrenia, psychosis-related disruption in
connectivity between certain regions, as an index of intrinsic functional disintegration, occurs …

Mechanisms for cognitive impairment in epilepsy: moving beyond seizures

MR Khalife, RC Scott, AE Hernan - Frontiers in neurology, 2022 - frontiersin.org
There has been a major emphasis on defining the role of seizures in the causation of
cognitive impairments like memory deficits in epilepsy. Here we focus on an alternative …

Impaired consciousness in patients with absence seizures investigated by functional MRI, EEG, and behavioural measures: a cross-sectional study

JN Guo, R Kim, Y Chen, M Negishi, S Jhun… - The Lancet …, 2016 - thelancet.com
Background The neural underpinnings of impaired consciousness and of the variable
severity of behavioural deficits from one absence seizure to the next are not well …

Considerations for resting state functional MRI and functional connectivity studies in rodents

WJ Pan, JCW Billings, JK Grooms, S Shakil… - Frontiers in …, 2015 - frontiersin.org
Resting state functional MRI (rs-fMRI) and functional connectivity map** have become
widely used tools in the human neuroimaging community and their use is rapidly spreading …

Reduced default mode network connectivity in treatment‐resistant idiopathic generalized epilepsy

BP Kay, MW DiFrancesco, MD Privitera, J Gotman… - …, 2013 - Wiley Online Library
Purpose Idiopathic generalized epilepsy (IGE) resistant to treatment is common, but its
neuronal correlates are not entirely understood. Therefore, the aim of this study was to …