Ether lipids from archaeas in nano-drug delivery and vaccination

EL Romero, MJ Morilla - International Journal of Pharmaceutics, 2023 - Elsevier
Archaea are microorganisms more closely related to eukaryotes than bacteria. Almost 50
years after being defined as a new domain of life on earth, new species continue to be …

Nanostructured lipid carriers for the formulation of topical anti-inflammatory nanomedicines based on natural substances

KCB Ferreira, ABCS Valle, CQ Paes, GD Tavares… - Pharmaceutics, 2021 - mdpi.com
The main function of the skin is to protect the body from the external environment. However,
the skin can undergo inflammatory processes, due to genetic, hormonal, or environmental …

Long-term consequence of non-neurotropic H3N2 influenza A virus infection for the progression of Alzheimer's disease symptoms

S Hosseini, K Michaelsen-Preusse… - Frontiers in cellular …, 2021 - frontiersin.org
Influenza viruses until today are a leading cause of worldwide severe pandemics and
represent a major threat to human and animal health. Although the primary target of …

The anti MRSA biofilm activity of Thymus vulgaris essential oil in nanovesicles

AP Perez, N Perez, CMS Lozano, MJ Altube… - Phytomedicine, 2019 - Elsevier
Background Thymus vulgaris essential oil (T) could be an alternative to classical antibiotics
against bacterial biofilms, which show increased tolerance to antibiotics and host defence …

Inhaled lipid nanocarriers for pulmonary delivery of glucocorticoids: Previous strategies, recent advances and key factors description

MJ Altube, N Perez, EL Romero, MJ Morilla… - International Journal of …, 2023 - Elsevier
In view of the strong anti-inflammatory activity of glucocorticoids (GC) they are used in the
treatment of almost all inflammatory lung diseases. In particular, inhaled GC (IGC) allow high …

Co-aerosolized pulmonary surfactant and ambroxol for COVID-19 ARDS intervention: what are we waiting for?

P Kumar - Frontiers in Bioengineering and Biotechnology, 2020 - frontiersin.org
After more than 225 days of the first reports of the novel coronavirus from China, COVID-19
pandemic is still on surge. The search for an effective and efficient therapeutic and …

Superoxide dismutase in nanoarchaeosomes for targeted delivery to inflammatory macrophages

P Schilrreff, YR Simioni, HE Jerez, AT Caimi… - Colloids and Surfaces B …, 2019 - Elsevier
Oxidative stress plays an essential role in the pathogenesis and progression of inflammatory
bowel disease. Co-administration of antioxidants and anti-inflammatory drugs has shown …

Role of surfactants in pulmonary drug delivery

PP Mehta, V Dhapte-Pawar - Green sustainable process for chemical and …, 2022 - Elsevier
In this article, we try to present a summary of the biosurfactant used in the treatment of life-
threatening pulmonary disease. Initially, different pulmonary diseases, pulmonary …

Macrophage apoptosis using alendronate in targeted nanoarchaeosomes

HE Jerez, MJ Altube, YB Gándola, L Gonzalez… - European Journal of …, 2021 - Elsevier
Nanoarchaeosomes are non-hydrolysable nanovesicles made of archaeolipids, naturally
functionalised with ligand for scavenger receptor class 1. We hypothesized that nitrogenate …

The anti-inflammatory effect of nanoarchaeosomes on human endothelial cells

N Charó, H Jerez, S Tatti, EL Romero, M Schattner - Pharmaceutics, 2022 - mdpi.com
Archaebacterias are considered a unique source of novel biomaterials of interest for
nanomedicine. In this perspective, the effects of nanoarchaeosomes (ARC), which are …