Strategies to address low drug solubility in discovery and development

HD Williams, NL Trevaskis, SA Charman… - Pharmacological …, 2013 - Elsevier
Drugs with low water solubility are predisposed to low and variable oral bioavailability and,
therefore, to variability in clinical response. Despite significant efforts to “design in” …

A multi-decadal view of seismic methods for detecting precursors of magma movement and eruption

BA Chouet, RS Matoza - Journal of Volcanology and Geothermal Research, 2013 - Elsevier
With the emergence of portable broadband seismic instrumentation, availability of digital
networks with wide dynamic range, and development of new powerful analysis techniques …

[HTML][HTML] Engineered feldspar-based ceramics: A review of their potential in ceramic industry

V Fuertes, JJ Reinosa, JF Fernández… - Journal of the European …, 2022 - Elsevier
Feldspars are the most abundant mineral in the earth's crust, however, their interest in
ceramic industry goes beyond their abundancy. The unique compositional and structural …

A review of smoothed particle hydrodynamics

M Bagheri, M Mohammadi, M Riazi - Computational Particle Mechanics, 2024 - Springer
Smoothed particle hydrodynamics (SPH) is an evolving computational fluid dynamics (CFD)
method. With time, it illustrates a great extent of its capabilities to be considered a practical …

Uphill diffusion in multicomponent mixtures

R Krishna - Chemical Society Reviews, 2015 - pubs.rsc.org
Molecular diffusion is an omnipresent phenomena that is important in a wide variety of
contexts in chemical, physical, and biological processes. In the majority of cases, the …

Pharmaceutical perspective on opalescence and liquid–liquid phase separation in protein solutions

AS Raut, DS Kalonia - Molecular Pharmaceutics, 2016 - ACS Publications
Opalescence in protein solutions reduces aesthetic appeal of a formulation and can be an
indicator of the presence of aggregates or precursor to phase separation in solution …

Graphene nanoplatelets based polyimide/Pebax dual-layer mixed matrix hollow fiber membranes for CO2/CH4 and He/N2 separations

GV Theodorakopoulos, DS Karousos… - International Journal of …, 2022 - Elsevier
Mixed matrix membranes are key in the preparation of stable, stretchy, durable and efficient
membranes for gas separation applications. To this aim, the perfect filler nanomaterials' …

Focused review on Cu–Ni–Sn spinodal alloys: from casting to additive manufacturing

B Sankar, C Vinay, J Vishnu, KV Shankar… - Metals and Materials …, 2023 - Springer
The present review article evaluates the research and progress status of Cu–Ni–Sn-based
spinodal alloys focussed on the methods and technologies implemented to enhance the …

Helium and hydrogen selective carbon hollow fiber membranes: The effect of pyrolysis isothermal time

EP Favvas, NS Heliopoulos, SK Papageorgiou… - Separation and …, 2015 - Elsevier
In the present study carbon molecular sieve (CMS) hollow fiber membranes have been
produced by using P84 co-polyimide as precursor material and Argon as inert gas at three …

Multiscale phase separations for hierarchically ordered macro/mesostructured metal oxides

C Jo, J Hwang, WG Lim, J Lim, K Hur… - Advanced …, 2018 - Wiley Online Library
Porous architectures play an important role in various applications of inorganic materials.
Several attempts to develop mesoporous materials with controlled macrostructures have …