Inflammatory response of nanoparticles: mechanisms, consequences, and strategies for mitigation

M Summer, R Ashraf, S Ali, H Bach, S Noor, Q Noor… - Chemosphere, 2024 - Elsevier
Numerous nano-dimensioned materials have been generated as a result of several
advancements in nanoscale science such as metallic nanoparticles (mNPs) which have …

Plant coumarins with anti-HIV activity: Isolation and mechanisms of action

AD Sharapov, RF Fatykhov, IA Khalymbadzha… - International Journal of …, 2023 - mdpi.com
This review summarizes and systematizes the literature on the anti-HIV activity of plant
coumarins with emphasis on isolation and the mechanism of their antiviral action. This …

[HTML][HTML] A review for cancer treatment with mushroom metabolites through targeting mitochondrial signaling pathway: In vitro and in vivo evaluations, clinical studies …

S Nandi, R Sikder, S Rapior, S Arnould… - Fitoterapia, 2024 - Elsevier
Resistance to apoptosis stands as a roadblock to the successful pharmacological execution
of anticancer drug effect. A comprehensive insight into apoptotic signaling pathways and an …

Chinese medicine in the treatment of ulcerative colitis: the mechanisms of signaling pathway regulations

S Zheng, T Xue, B Wang, H Guo… - The American Journal of …, 2022 - World Scientific
Ulcerative colitis (UC) is a common clinical inflammatory bowel disease characterized by
repeated attacks, difficult treatment, and great harm to the physical and mental health of the …

Investigation on the mechanisms by which the herbal remedies induce anti-prostate cancer activity: uncovering the most practical natural compound

A Poustforoosh, S Faramarz… - Journal of …, 2024 - Taylor & Francis
Prostate cancer (PCa) is one of the most reported cancers among men worldwide. Targeting
the essential proteins associated with PCa could be a promising method for cancer …

Osthole: A potential AMPK agonist that inhibits NLRP3 inflammasome activation by regulating mitochondrial homeostasis for combating rheumatoid arthritis

X Jiang, Z Lu, Q Zhang, J Yu, D Han, J Liu, P Li, F Li - Phytomedicine, 2023 - Elsevier
Background Osthole (OST), a characteristic coumarin compound in Angelicae pubescentis
radix (APR), has shown potent efficacy in the treatment of rheumatoid arthritis (RA), but its …

Signaling pathways involved in the neuroprotective effect of osthole: evidence and mechanisms

L Singh, R Bhatti - Molecular neurobiology, 2024 - Springer
Neurodegenerative diseases constitute a major threat to human health and are usually
accompanied by progressive structural and functional loss of neurons. Abnormalities in …

Momordica charantia polysaccharide ameliorates D-galactose-induced aging through the Nrf2/β-Catenin signaling pathway

J Yue, P Guo, Y **, M Li, X Hu, W Wang, X Wei… - Metabolic Brain …, 2023 - Springer
Aging is widely thought to be associated with oxidative stress. Momordica charantia (MC) is
a classic vegetable and traditional herbal medicine widely consumed in Asia, and M …

From preclinical stroke models to humans: Polyphenols in the prevention and treatment of stroke

E Parrella, C Gussago, V Porrini, M Benarese, M Pizzi - Nutrients, 2020 - mdpi.com
Polyphenols are an important family of molecules of vegetal origin present in many
medicinal and edible plants, which represent important alimentary sources in the human …

Osthole: An up-to-date review of its anticancer potential and mechanisms of action

S Yang, W Dai, J Wang, X Zhang, Y Zheng… - Frontiers in …, 2022 - frontiersin.org
With its high incidence and mortality rates, cancer is one of the largest health problems
worldwide. Investigating various cancer treatment options has been the focus of many …