Magnitude and heterogeneity of brain structural abnormalities in 22q11. 2 deletion syndrome: a meta-analysis

M Rogdaki, M Gudbrandsen, RA McCutcheon… - Molecular …, 2020 - nature.com
Abstract The 22q11. 2 deletion syndrome (22q11. 2DS) is a neurodevelopmental disorder
associated with a number of volumetric brain abnormalities. The syndrome is also …

Neuroanatomical Correlates of Cognitive Dysfunction in 22q11. 2 Deletion Syndrome

S Smerconish, JE Schmitt - Genes, 2024 - mdpi.com
22q11. 2 Deletion Syndrome (22q11. 2DS), the most common chromosomal microdeletion,
presents as a heterogeneous phenotype characterized by an array of anatomical …

Positive psychotic symptoms are associated with divergent developmental trajectories of hippocampal volume during late adolescence in patients with 22q11DS

V Mancini, C Sandini, MC Padula, D Zöller… - Molecular …, 2020 - nature.com
Low hippocampal volume is a consistent finding in schizophrenia and across the psychosis
spectrum. However, there is a lack of studies investigating longitudinal hippocampal …

Sleep problems and associations with psychopathology and cognition in young people with 22q11. 2 deletion syndrome (22q11. 2DS)

HA Moulding, U Bartsch, J Hall, MW Jones… - Psychological …, 2020 - cambridge.org
BackgroundYoung people with 22q11. 2 deletion syndrome (22q11. 2DS) are at high risk for
neurodevelopmental disorders. Sleep problems may play a role in this risk but their …

Current and potential pharmacological and psychosocial interventions for anxiety symptoms and disorders in patients with schizophrenia: structured review

FM Howells, DG Kingdon… - … Clinical and Experimental, 2017 - Wiley Online Library
Abstract Objective Between 30% and 62% of patients with schizophrenia present with co‐
morbid anxiety disorders that are associated with increased overall burden. Our aim was to …

An initial investigation of neonatal neuroanatomy, caregiving, and levels of disorganized behavior

A Rifkin-Graboi, HM Tan, GKY Shaun… - Proceedings of the …, 2019 - National Acad Sciences
Attachment disorganization is a risk factor for difficulties in attention, social relationships, and
mental health. Conceptually, attachment disorganization may indicate a breakdown in fear …

Modular, circuit-based interventions rescue hippocampal-dependent social and spatial memory in a 22q11. 2 deletion syndrome mouse model

JB Kahn, RG Port, SA Anderson, DA Coulter - Biological psychiatry, 2020 - Elsevier
Abstract Background 22q11. 2 deletion syndrome (22qDS) manifests with myriad symptoms,
including multiple neuropsychiatric disorders. Complications associated with the polygenic …

Pituitary dysmaturation affects psychopathology and neurodevelopment in 22q11. 2 Deletion Syndrome

C Sandini, M Chambaz, M Schneider… - …, 2020 - Elsevier
Abstract Background 22q11. 2 Deletion Syndrome (22q11DS) confers strongly increased
genetic risk for multiple psychiatric disorders. Similarly to the general population, rates of …

Baseline connectome modular abnormalities in the childhood phase of a longitudinal study on individuals with chromosome 22q11. 2 deletion syndrome

L Zhan, LM Jenkins, A Zhang, G Conte… - Human brain …, 2018 - Wiley Online Library
Occurring in at least 1 in 3,000 live births, chromosome 22q11. 2 deletion syndrome
(22q11DS) produces a complex phenotype that includes a constellation of medical …

[HTML][HTML] Interhemispheric CA1 projections support spatial cognition and are affected in a mouse model of the 22q11. 2 deletion syndrome

NS de León Reyes, MH Bortolozzo-Gleich… - …, 2024 - pmc.ncbi.nlm.nih.gov
Untangling the hippocampus connectivity is critical for understanding the mechanisms
supporting learning and memory. However, the function of interhemispheric connections …