Recent developments of useful MALDI matrices for the mass spectrometric characterization of lipids

J Leopold, Y Popkova, KM Engel, J Schiller - Biomolecules, 2018 - mdpi.com
Matrix-assisted laser desorption/ionization (MALDI) is one of the most successful “soft”
ionization methods in the field of mass spectrometry and enables the analysis of a broad …

Recent advances in analytical strategies for mass spectrometry-based lipidomics

T Xu, C Hu, Q Xuan, G Xu - Analytica chimica acta, 2020 - Elsevier
Lipids are vital biological molecules and play multiple roles in cellular function of
mammalian organisms such as cellular membrane anchoring, signal transduction, material …

Lipidomics in pathogenesis, progression and treatment of nonalcoholic steatohepatitis (NASH): Recent advances

G Musso, F Saba, M Cassader, R Gambino - Progress in Lipid Research, 2023 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) is a chronic liver disease affecting up to 30% of the
general adult population. NAFLD encompasses a histological spectrum ranging from pure …

A new update of MALDI-TOF mass spectrometry in lipid research

KM Engel, P Prabutzki, J Leopold, A Nimptsch… - Progress in lipid …, 2022 - Elsevier
Matrix-assisted laser desorption and ionization (MALDI) mass spectrometry (MS) is an
indispensable tool in modern lipid research since it is fast, sensitive, tolerates sample …

Mass spectrometry‐based lipidomics in food science and nutritional health: A comprehensive review

T Sun, X Wang, P Cong, J Xu… - … Reviews in Food Science …, 2020 - Wiley Online Library
With the advance in science and technology as well as the improvement of living standards,
the function of food is no longer just to meet the needs of survival. Food science and its …

[HTML][HTML] Clinical lipidomics: realizing the potential of lipid profiling

TG Meikle, K Huynh, C Giles, PJ Meikle - Journal of Lipid Research, 2021 - Elsevier
Dysregulation of lipid metabolism plays a major role in the etiology and sequelae of
inflammatory disorders, cardiometabolic and neurological diseases, and several forms of …

Administration of exogenous melatonin improves the diurnal rhythms of the gut microbiota in mice fed a high-fat diet

J Yin, Y Li, H Han, J Ma, G Liu, X Wu, X Huang… - Msystems, 2020 - journals.asm.org
Melatonin, a circadian hormone, has been reported to improve host lipid metabolism by
reprogramming the gut microbiota, which also exhibits rhythmicity in a light/dark cycle …

From big data to big insights: statistical and bioinformatic approaches for exploring the lipidome

JR Chappel, KI Kirkwood-Donelson, DM Reif… - Analytical and …, 2024 - Springer
The goal of lipidomic studies is to provide a broad characterization of cellular lipids present
and changing in a sample of interest. Recent lipidomic research has significantly contributed …

Plasma lipidomic profiling reveals six candidate biomarkers for the prediction of incident stroke in patients with hypertension

J Zeng, R Zhang, T Zhao, H Wang, L Han, L Pu… - Metabolomics, 2024 - Springer
Introduction The burden of stroke in patients with hypertension is very high, and its
prediction is critical. Objectives We aimed to use plasma lipidomics profiling to identify lipid …

[HTML][HTML] Changes in the cerebrospinal fluid and plasma lipidome in patients with Rett syndrome

M Zandl-Lang, T Züllig, M Trötzmüller, Y Naegelin… - Metabolites, 2022 - mdpi.com
Rett syndrome (RTT) is defined as a rare disease caused by mutations of the methyl-CpG
binding protein 2 (MECP2). It is one of the most common causes of genetic mental …