Copper metabolism in cell death and autophagy

Q Xue, R Kang, DJ Klionsky, D Tang, J Liu, X Chen - Autophagy, 2023 - Taylor & Francis
Copper is an essential trace element in biological systems, maintaining the activity of
enzymes and the function of transcription factors. However, at high concentrations, copper …

Targeting the progression of chronic kidney disease

M Ruiz-Ortega, S Rayego-Mateos, S Lamas… - Nature Reviews …, 2020 - nature.com
Chronic kidney disease (CKD) is a devastating condition that is reaching epidemic levels
owing to the increasing prevalence of diabetes mellitus, hypertension and obesity, as well …

Programmed cell death in atherosclerosis and vascular calcification

M Li, ZW Wang, LJ Fang, SQ Cheng, X Wang… - Cell death & …, 2022 - nature.com
The concept of cell death has been expanded beyond apoptosis and necrosis to additional
forms, including necroptosis, pyroptosis, autophagy, and ferroptosis. These cell death …

How autophagy controls the intestinal epithelial barrier

EG Foerster, T Mukherjee, L Cabral-Fernandes… - Autophagy, 2022 - Taylor & Francis
Macroautophagy/autophagy is a cellular catabolic process that results in lysosome-
mediated recycling of organelles and protein aggregates, as well as the destruction of …

Tumor associated neutrophils. Their role in tumorigenesis, metastasis, prognosis and therapy

MT Masucci, M Minopoli, MV Carriero - Frontiers in oncology, 2019 - frontiersin.org
Tumor Associated Neutrophils (TANs) are engaged into the tumor microenvironment by
cytokines and chemokines, can be distinguished according to their activation and cytokine …

The roles of autophagy in cancer

CW Yun, SH Lee - International journal of molecular sciences, 2018 - mdpi.com
Autophagy is an intracellular degradative process that occurs under several stressful
conditions, including organelle damage, the presence of abnormal proteins, and nutrient …

The regulation, function, and role of lipophagy, a form of selective autophagy, in metabolic disorders

S Zhang, X Peng, S Yang, X Li, M Huang, S Wei… - Cell death & …, 2022 - nature.com
Autophagy is a conserved method of quality control in which cytoplasmic contents are
degraded via lysosomes. Lipophagy, a form of selective autophagy and a novel type of lipid …

Current knowledge on exosome biogenesis and release

NP Hessvik, A Llorente - Cellular and Molecular Life Sciences, 2018 - Springer
Exosomes are nanosized membrane vesicles released by fusion of an organelle of the
endocytic pathway, the multivesicular body, with the plasma membrane. This process was …

Exosomal lipid composition and the role of ether lipids and phosphoinositides in exosome biology

T Skotland, NP Hessvik, K Sandvig, A Llorente - Journal of lipid research, 2019 - ASBMB
Exosomes are a type of extracellular vesicle released from cells after fusion of multivesicular
bodies with the plasma membrane. These vesicles are often enriched in cholesterol, SM …

Guidelines for the use of flow cytometry and cell sorting in immunological studies

A Cossarizza, HD Chang, A Radbruch… - European journal of …, 2019 - Wiley Online Library
These guidelines are a consensus work of a considerable number of members of the
immunology and flow cytometry community. They provide the theory and key practical …