Development of therapeutic antibodies for the treatment of diseases
It has been more than three decades since the first monoclonal antibody was approved by
the United States Food and Drug Administration (US FDA) in 1986, and during this time …
the United States Food and Drug Administration (US FDA) in 1986, and during this time …
Coronavirus infections in children including COVID-19: an overview of the epidemiology, clinical features, diagnosis, treatment and prevention options in children
Coronaviruses (CoVs) are a large family of enveloped, single-stranded, zoonotic RNA
viruses. Four CoVs commonly circulate among humans: HCoV2-229E,-HKU1,-NL63 and …
viruses. Four CoVs commonly circulate among humans: HCoV2-229E,-HKU1,-NL63 and …
[HTML][HTML] Tracking changes in SARS-CoV-2 spike: evidence that D614G increases infectivity of the COVID-19 virus
A SARS-CoV-2 variant carrying the Spike protein amino acid change D614G has become
the most prevalent form in the global pandemic. Dynamic tracking of variant frequencies …
the most prevalent form in the global pandemic. Dynamic tracking of variant frequencies …
Potently neutralizing and protective human antibodies against SARS-CoV-2
The ongoing pandemic of coronavirus disease 2019 (COVID-19), which is caused by severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a major threat to global health …
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a major threat to global health …
SARS and MERS: recent insights into emerging coronaviruses
E De Wit, N Van Doremalen, D Falzarano… - Nature reviews …, 2016 - nature.com
Abstract The emergence of Middle East respiratory syndrome coronavirus (MERS-CoV) in
2012 marked the second introduction of a highly pathogenic coronavirus into the human …
2012 marked the second introduction of a highly pathogenic coronavirus into the human …
Coronavirus vaccine development: from SARS and MERS to COVID-19
Abstract Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a new type of
coronavirus that causes the Coronavirus Disease 2019 (COVID-19), which has been the …
coronavirus that causes the Coronavirus Disease 2019 (COVID-19), which has been the …
Potent neutralizing antibodies from COVID-19 patients define multiple targets of vulnerability
The rapid spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has
had a large impact on global health, travel, and economy. Therefore, preventative and …
had a large impact on global health, travel, and economy. Therefore, preventative and …
The dawn of mRNA vaccines: The COVID-19 case
In less than one year since the outbreak of the COVID-19 pandemic, two mRNA-based
vaccines, BNT162b2 and mRNA-1273, were granted the first historic authorization for …
vaccines, BNT162b2 and mRNA-1273, were granted the first historic authorization for …
Insights into the recent 2019 novel coronavirus (SARS-CoV-2) in light of past human coronavirus outbreaks
Coronaviruses (CoVs) are RNA viruses that have become a major public health concern
since the Severe Acute Respiratory Syndrome-CoV (SARS-CoV) outbreak in 2002. The …
since the Severe Acute Respiratory Syndrome-CoV (SARS-CoV) outbreak in 2002. The …
Coronaviruses—drug discovery and therapeutic options
In humans, infections with the human coronavirus (HCoV) strains HCoV-229E, HCoV-OC43,
HCoV-NL63 and HCoV-HKU1 usually result in mild, self-limiting upper respiratory tract …
HCoV-NL63 and HCoV-HKU1 usually result in mild, self-limiting upper respiratory tract …