[HTML][HTML] The role of renal hypoxia in the pathogenesis of diabetic kidney disease: a promising target for newer renoprotective agents including SGLT2 inhibitors?
Diabetic kidney disease is the most common cause of end-stage kidney disease and poses
a major global health problem. Finding new, safe, and effective strategies to halt this disease …
a major global health problem. Finding new, safe, and effective strategies to halt this disease …
Basic principles and new advances in kidney imaging
A Caroli, A Remuzzi, LO Lerman - Kidney international, 2021 - Elsevier
Over the past few years, clinical renal imaging has seen great advances, allowing
assessments of kidney structure and morphology, perfusion, function and metabolism, and …
assessments of kidney structure and morphology, perfusion, function and metabolism, and …
Consensus-based technical recommendations for clinical translation of renal ASL MRI
Objectives This study aimed at develo** technical recommendations for the acquisition,
processing and analysis of renal ASL data in the human kidney at 1.5 T and 3 T field …
processing and analysis of renal ASL data in the human kidney at 1.5 T and 3 T field …
Acute effects of dapagliflozin on renal oxygenation and perfusion in type 1 diabetes with albuminuria: a randomised, double-blind, placebo-controlled crossover trial
JC Laursen, N Søndergaard-Heinrich… - …, 2021 - thelancet.com
Background Inhibitors of the sodium-glucose cotransporter 2 (SGLT2) slow the progression
of diabetic kidney disease, possibly by reducing the proximal tubule transport workload with …
of diabetic kidney disease, possibly by reducing the proximal tubule transport workload with …
Continuous bladder urinary oxygen tension as a new tool to monitor medullary oxygenation in the critically ill
Acute kidney injury (AKI) is common in the critically ill. Inadequate renal medullary tissue
oxygenation has been linked to its pathogenesis. Moreover, renal medullary tissue hypoxia …
oxygenation has been linked to its pathogenesis. Moreover, renal medullary tissue hypoxia …
Magnetic resonance imaging assessment of renal flow distribution patterns during ex vivo normothermic machine perfusion in porcine and human kidneys
R Schutter, VA Lantinga, TL Hamelink… - Transplant …, 2021 - Wiley Online Library
Acceptance criteria of deceased donor organs have gradually been extended toward
suboptimal quality, posing an urgent need for more objective pre‐transplant organ …
suboptimal quality, posing an urgent need for more objective pre‐transplant organ …
Decreased renal perfusion during acute kidney injury in critical COVID-19 assessed by magnetic resonance imaging: a prospective case control study
Background Renal hypoperfusion has been suggested to contribute to the development of
acute kidney injury (AKI) in critical COVID-19. However, limited data exist to support this. We …
acute kidney injury (AKI) in critical COVID-19. However, limited data exist to support this. We …
Novel approaches in chronic renal failure without renal replacement therapy: a review
SL Martínez-Hernández, MH Muñoz-Ortega… - Biomedicines, 2023 - mdpi.com
Chronic kidney disease (CKD) is characterized by renal parenchymal damage leading to a
reduction in the glomerular filtration rate. The inflammatory response plays a pivotal role in …
reduction in the glomerular filtration rate. The inflammatory response plays a pivotal role in …
MRI‐based quantification of whole‐organ renal metabolic rate of oxygen
RS Deshpande, MC Langham, K Susztak… - NMR in …, 2024 - Wiley Online Library
During the early stages of diabetes, kidney oxygen utilization increases. The mismatch
between oxygen demand and supply contributes to tissue hypoxia, a key driver of chronic …
between oxygen demand and supply contributes to tissue hypoxia, a key driver of chronic …
GLP− 1 Promotes Cortical and Medullary Perfusion in the Human Kidney and Maintains Renal Oxygenation During NaCl Loading
B Haddock, KB Kristensen, M Tayyab… - Journal of the …, 2023 - Am Heart Assoc
Background GLP‐1 (glucagon‐like peptide‐1) receptor agonists exert beneficial long‐term
effects on cardiovascular and renal outcomes. In humans, the natriuretic effect of GLP‐1 …
effects on cardiovascular and renal outcomes. In humans, the natriuretic effect of GLP‐1 …