Kléber, André G., and Yoram Rudy. Basic Mechanisms of Cardiac Impulse Propagation and
Associated Arrhythmias. Physiol Rev 84: 431–488, 2004; 10.1152/physrev. 00025.2003 …

This article focuses on the regional heterogeneity of the mammalian sinoatrial (SA) node in
terms of cell morphology, pacemaker activity, action potential configuration and conduction …

The mechanisms underlying many important properties of the human atrial action potential
(AP) are poorly understood. Using specific formulations of the K+, Na+, and Ca2+ currents …

The heart automaticity is a fundamental physiological function in higher organisms. The
spontaneous activity is initiated by specialized populations of cardiac cells generating …

In a normal human life span, the heart beats about 2–3 billion times. Under diseased
conditions, a heart may lose its normal rhythm and degenerate suddenly into much faster …

Mathematical models of the action potential in the periphery and center of the rabbit
sinoatrial (SA) node have been developed on the basis of published experimental data …

This book on modelling the electrical activity of the heart is an attempt to describe continuum
based modelling of cardiac electrical activity from the cell level to the body surface (the …

Known as the bible of biomedical engineering, The Biomedical Engineering Handbook,
Fourth Edition, sets the standard against which all other references of this nature are …

We developed an improved mathematical model for a single primary pacemaker cell of the
rabbit sinoatrial node. Original features of our model include 1) incorporation of the …

In this manuscript we review the state of cardiac cell modelling in the context of international
initiatives such as the IUPS Physiome and Virtual Physiological Human Projects, which aim …