Antibacterial nanomaterials: mechanisms, impacts on antimicrobial resistance and design principles
Antimicrobial resistance (AMR) is one of the biggest threats to the environment and health.
AMR rapidly invalidates conventional antibiotics, and antimicrobial nanomaterials have …
AMR rapidly invalidates conventional antibiotics, and antimicrobial nanomaterials have …
Engineering mesoporous silica nanoparticles for drug delivery: where are we after two decades?
The present review details a chronological description of the events that took place during
the development of mesoporous materials, their different synthetic routes and their use as …
the development of mesoporous materials, their different synthetic routes and their use as …
[HTML][HTML] Biosafety of mesoporous silica nanoparticles; towards clinical translation
A Lérida-Viso, A Estepa-Fernández… - Advanced Drug Delivery …, 2023 - Elsevier
Mesoporous silica nanoparticles (MSNs) have attracted the attention of chemists, who have
developed numerous systems for the encapsulation of a plethora of molecules, allowing the …
developed numerous systems for the encapsulation of a plethora of molecules, allowing the …
[HTML][HTML] Silica nanoparticles: A review of their safety and current strategies to overcome biological barriers
Silica nanoparticles (SNP) have gained tremendous attention in the recent decades. They
have been used in many different biomedical fields including diagnosis, biosensing and …
have been used in many different biomedical fields including diagnosis, biosensing and …
Bioinspired nanotopographical design of drug delivery systems
Effective drug delivery is important in the treatment of various biomedical conditions, ranging
from autoimmune disorders to cancer and bacterial infections. Nanostructured systems can …
from autoimmune disorders to cancer and bacterial infections. Nanostructured systems can …
Macrophage-membrane-camouflaged nonviral gene vectors for the treatment of multidrug-resistant bacterial sepsis
H Cao, Y Gao, H Jia, L Zhang, J Liu, G Mu, H Gui… - Nano Letters, 2022 - ACS Publications
Sepsis is a life-threatening disease caused by systemic bacterial infections, with high
morbidity and mortality worldwide. As the standard treatment for sepsis, antibiotic therapy …
morbidity and mortality worldwide. As the standard treatment for sepsis, antibiotic therapy …
Nanoparticles exhibiting virus-mimic surface topology for enhanced oral delivery
Z Sang, L Xu, R Ding, M Wang, X Yang, X Li… - Nature …, 2023 - nature.com
The oral delivery of nano-drug delivery systems (Nano-DDS) remains a challenge. Taking
inspirations from viruses, here we construct core–shell mesoporous silica nanoparticles …
inspirations from viruses, here we construct core–shell mesoporous silica nanoparticles …
Site-selective superassembly of biomimetic nanorobots enabling deep penetration into tumor with stiff stroma
M Yan, Q Chen, T Liu, X Li, P Pei, L Zhou… - Nature …, 2023 - nature.com
Chemotherapy remains as the first-choice treatment option for triple-negative breast cancer
(TNBC). However, the limited tumor penetration and low cellular internalization efficiency of …
(TNBC). However, the limited tumor penetration and low cellular internalization efficiency of …
Powering mesoporous silica nanoparticles into bioactive nanoplatforms for antibacterial therapies: strategies and challenges
B Li, Y Liao, X Su, S Chen, X Wang, B Shen… - Journal of …, 2023 - Springer
Bacterial infection has been a major threat to worldwide human health, in particular with the
ever-increasing level of antimicrobial resistance. Given the complex microenvironment of …
ever-increasing level of antimicrobial resistance. Given the complex microenvironment of …
Glutathione-Exhausting Nanoprobes for NIR-II fluorescence imaging-guided surgery and boosting Radiation Therapy Efficacy via Ferroptosis in breast Cancer
Breast-conserving surgery (BCS) is the standard of care for early breast cancer patients,
while the high ratio of reoperation is still a challenge due to inaccurate margin assessments …
while the high ratio of reoperation is still a challenge due to inaccurate margin assessments …