Occurrence, genotoxicity, and carcinogenicity of regulated and emerging disinfection by-products in drinking water: a review and roadmap for research
Disinfection by-products (DBPs) are formed when disinfectants (chlorine, ozone, chlorine
dioxide, or chloramines) react with naturally occurring organic matter, anthropogenic …
dioxide, or chloramines) react with naturally occurring organic matter, anthropogenic …
Endogenous DNA damage in humans: a review of quantitative data
R De Bont, N Van Larebeke - Mutagenesis, 2004 - academic.oup.com
DNA damage plays a major role in mutagenesis, carcinogenesis and ageing. The vast
majority of mutations in human tissues are certainly of endogenous origin. A thorough …
majority of mutations in human tissues are certainly of endogenous origin. A thorough …
Aldehyde sources, metabolism, molecular toxicity mechanisms, and possible effects on human health
PJ O'Brien, AG Siraki, N Shangari - Critical reviews in toxicology, 2005 - Taylor & Francis
Aldehydes are organic compounds that are widespread in nature. They can be formed
endogenously by lipid peroxidation (LPO), carbohydrate or metabolism ascorbate …
endogenously by lipid peroxidation (LPO), carbohydrate or metabolism ascorbate …
[HTML][HTML] Glycation damage: a possible hub for major pathophysiological disorders and aging
M Fournet, F Bonté, A Desmoulière - Aging and disease, 2018 - ncbi.nlm.nih.gov
Glycation is both a physiological and pathological process which mainly affects proteins,
nucleic acids and lipids. Exogenous and endogenous glycation produces deleterious …
nucleic acids and lipids. Exogenous and endogenous glycation produces deleterious …
Mechanistic targeting of advanced glycation end-products in age-related diseases
S Rowan, E Bejarano, A Taylor - … et Biophysica Acta (BBA)-Molecular Basis …, 2018 - Elsevier
Glycative stress, caused by the accumulation of cytotoxic and irreversibly-formed sugar-
derived advanced glycation end-products (AGEs), contributes to morbidity associated with …
derived advanced glycation end-products (AGEs), contributes to morbidity associated with …
Mammalian cell cytotoxicity and genotoxicity analysis of drinking water disinfection by‐products
MJ Plewa, Y Kargalioglu, D Vankerk… - Environmental and …, 2002 - Wiley Online Library
Cytotoxicity and genotoxicity assays were used to analyze drinking water disinfection by‐
products (DBPs) in Chinese hamster ovary (CHO) AS52 cells. The DBPs were chosen …
products (DBPs) in Chinese hamster ovary (CHO) AS52 cells. The DBPs were chosen …
AGEs, RAGEs and s-RAGE; friend or foe for cancer
Impaired awareness of glycation biology in cancer initiation and progression is one of the
fundamental reasons for its meticulous investigation of the molecules involved in signalling …
fundamental reasons for its meticulous investigation of the molecules involved in signalling …
Obesity: A perfect storm for carcinogenesis
BHL Harris, VM Macaulay, DA Harris… - Cancer and Metastasis …, 2022 - Springer
Obesity-related cancers account for 40% of the cancer cases observed in the USA and
obesity is overtaking smoking as the most widespread modifiable risk factor for …
obesity is overtaking smoking as the most widespread modifiable risk factor for …
DNA damage induced by endogenous aldehydes: current state of knowledge
DNA damage plays a major role in various pathophysiological conditions including
carcinogenesis, aging, inflammation, diabetes and neurodegenerative diseases. Oxidative …
carcinogenesis, aging, inflammation, diabetes and neurodegenerative diseases. Oxidative …
α‐Dicarbonyl compounds in food products: Comprehensively understanding their occurrence, analysis, and control
S Yan, L Wu, X Xue - … Reviews in Food Science and Food …, 2023 - Wiley Online Library
Abstract α‐Dicarbonyl compounds (α‐DCs) are readily produced during the heating and
storage of foods, mainly through the Maillard reaction, caramelization, lipid‐peroxidation …
storage of foods, mainly through the Maillard reaction, caramelization, lipid‐peroxidation …