Unveiling the connection: long-chain non-coding RNAs and critical signaling pathways in breast cancer

R Thapa, O Afzal, G Gupta, AA Bhat, WH Almalki… - … -Research and Practice, 2023 - Elsevier
Breast cancer is a complex and diverse condition that disrupts multiple signaling pathways
essential for cell proliferation, survival, and differentiation. Recently, the significant …

Sodium alginate based drug delivery in management of breast cancer

MAJ Shaikh, KS Alharbi, WH Almalki, SS Imam… - Carbohydrate …, 2022 - Elsevier
Among women, breast cancer (B· C.) is a common form of cancer that can strike either
developed or develo** countries. In addition to pregnancy-related variables, hormone …

The complex role of MEG3: an emerging long non-coding RNA in breast cancer

MS Hussain, AA Majami, H Ali, G Gupta… - … -Research and Practice, 2023 - Elsevier
MEG3, a significant long non-coding RNA (lncRNA), substantially functions in diverse
biological processes, particularly breast cancer (BC) development. Within the imprinting …

Unraveling the impact of miR-21 on apoptosis regulation in glioblastoma

MAJ Shaikh, ASA Altamimi, M Afzal, G Gupta… - … -Research and Practice, 2024 - Elsevier
Glioblastoma is a prevalent form of carcinoma that exhibits a greater incidence rate across
diverse demographics globally. Despite extensive global efforts, GBM continues to be a …

Circular RNAs in the KRAS pathway: emerging players in cancer progression

MS Hussain, E Moglad, M Afzal, P Bansal… - … -Research and Practice, 2024 - Elsevier
Circular RNAs (circRNAs) have been recognized as key components in the intricate
regulatory network of the KRAS pathway across various cancers. The KRAS pathway, a …

Role of medicinal plant‐derived nutraceuticals as a potential target for the treatment of breast cancer

KS Alharbi, WH Almalki, HA Makeen… - Journal of Food …, 2022 - Wiley Online Library
Breast cancer (BC) is one of the most challenging cancers to treat, accounting for many
cancer‐related deaths. Over some years, chemotherapy, hormone treatment, radiation, and …

An overview of epithelial growth factor receptor (EGFR) inhibitors in cancer therapy

KS Alharbi, MAJ Shaikh, O Afzal, ASA Altamimi… - Chemico-Biological …, 2022 - Elsevier
Epithelial growth factor receptor (EGFR), a transmembrane receptor on the cell surface,
carries extracellular messages into the cell and alters the activity of the nucleus through …

Emerging role of tumor suppressing microRNAs as therapeutics in managing non-small cell lung cancer

S Singh, S Saxena, H Sharma, KR Paudel… - … -Research and Practice, 2024 - Elsevier
Lung cancer (LC) is the second leading cause of death across the globe after breast cancer.
There are two types of LC viz. small cell lung cancer (SCLC) and non-small cell lung cancer …

MicroRNA-21's role in PTEN suppression and PI3K/AKT activation: Implications for cancer biology

HS Chawra, M Agarwal, A Mishra, SS Chandel… - … -Research and Practice, 2024 - Elsevier
Abstract MicroRNA-21 (miR-21) was recognized as a key figure in the intricate web of tumor
biology, with a prominent role in regulating the PTEN tumor suppressor gene and the …

Perspectives and advancements in the design of nanomaterials for targeted cancer theranostics

YY Tan, PK Yap, GLX Lim, M Mehta, Y Chan… - Chemico-biological …, 2020 - Elsevier
Cancer continues to be one of the most challenging diseases to be treated and is one of the
leading causes of deaths around the globe. Cancers account for 13% of all deaths each …